Cell type-specific histone acetylation profiling of Alzheimer’s disease subjects and integration with genetics

Cell type-specific histone acetylation profiling of Alzheimer’s disease subjects and integration with genetics

<jats:p>We profile genome-wide histone 3 lysine 27 acetylation (H3K27ac) of 3 major brain cell types from hippocampus and dorsolateral prefrontal cortex (dlPFC) of subjects with and without Alzheimer’s Disease (AD). We confirm that single nucleotide polymorphisms (SNPs) associated with late on...

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Bibliographic Details
Main Authors: Ramamurthy, Easwaran, Welch, Gwyneth, Cheng, Jemmie, Yuan, Yixin, Gunsalus, Laura, Bennett, David A, Tsai, Li-Huei, Pfenning, Andreas R
Other Authors: Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences
Format: Article
Language:English
Published: Frontiers Media SA 2023
Online Access:https://hdl.handle.net/1721.1/150408

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