Recording and Quantifying C. elegans Behavior
Studies of C. elegans behavior have been crucial in identifying genetic pathways that control nervous system development and function, as well as basic principles of neural circuit function. Modern analysis of C. elegans behavior commonly relies on video recordings of animals, followed by automated...
| Main Authors: | , |
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| Other Authors: | |
| Format: | Article |
| Language: | English |
| Published: |
Springer US
2023
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| Online Access: | https://hdl.handle.net/1721.1/150454 |
| _version_ | 1826203800288886784 |
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| author | Pokala, Navin Flavell, Steven W |
| author2 | Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences |
| author_facet | Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences Pokala, Navin Flavell, Steven W |
| author_sort | Pokala, Navin |
| collection | MIT |
| description | Studies of C. elegans behavior have been crucial in identifying genetic pathways that control nervous system development and function, as well as basic principles of neural circuit function. Modern analysis of C. elegans behavior commonly relies on video recordings of animals, followed by automated image analysis and behavior quantification. Here, we describe two methods for recording and quantifying C. elegans behavior: a single-worm tracking approach that provides high-resolution behavioral data for individual animals and a multi-worm tracking approach that allows for quantification of the behavior of many animals in parallel. These approaches should be useful to a wide range of researchers studying the nervous system and behavior of C. elegans. |
| first_indexed | 2024-09-23T12:43:14Z |
| format | Article |
| id | mit-1721.1/150454 |
| institution | Massachusetts Institute of Technology |
| language | English |
| last_indexed | 2025-02-19T04:21:45Z |
| publishDate | 2023 |
| publisher | Springer US |
| record_format | dspace |
| spelling | mit-1721.1/1504542025-01-04T05:08:53Z Recording and Quantifying C. elegans Behavior Pokala, Navin Flavell, Steven W Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences Studies of C. elegans behavior have been crucial in identifying genetic pathways that control nervous system development and function, as well as basic principles of neural circuit function. Modern analysis of C. elegans behavior commonly relies on video recordings of animals, followed by automated image analysis and behavior quantification. Here, we describe two methods for recording and quantifying C. elegans behavior: a single-worm tracking approach that provides high-resolution behavioral data for individual animals and a multi-worm tracking approach that allows for quantification of the behavior of many animals in parallel. These approaches should be useful to a wide range of researchers studying the nervous system and behavior of C. elegans. 2023-04-07T12:56:41Z 2023-04-07T12:56:41Z 2022 2023-04-07T12:50:20Z Article http://purl.org/eprint/type/BookItem https://hdl.handle.net/1721.1/150454 Pokala, Navin and Flavell, Steven W. 2022. "Recording and Quantifying C. elegans Behavior." 2468. en 10.1007/978-1-0716-2181-3_20 Creative Commons Attribution-Noncommercial-Share Alike https://creativecommons.org/licenses/by-nc-sa/4.0/ application/pdf Springer US Flavell |
| spellingShingle | Pokala, Navin Flavell, Steven W Recording and Quantifying C. elegans Behavior |
| title | Recording and Quantifying C. elegans Behavior |
| title_full | Recording and Quantifying C. elegans Behavior |
| title_fullStr | Recording and Quantifying C. elegans Behavior |
| title_full_unstemmed | Recording and Quantifying C. elegans Behavior |
| title_short | Recording and Quantifying C. elegans Behavior |
| title_sort | recording and quantifying c elegans behavior |
| url | https://hdl.handle.net/1721.1/150454 |
| work_keys_str_mv | AT pokalanavin recordingandquantifyingcelegansbehavior AT flavellstevenw recordingandquantifyingcelegansbehavior |