Extracting particle size distribution from laser speckle with a physics-enhanced autocorrelation-based estimator (PEACE)

<jats:title>Abstract</jats:title><jats:p>Extracting quantitative information about highly scattering surfaces from an imaging system is challenging because the phase of the scattered light undergoes multiple folds upon propagation, resulting in complex speckle patterns. One specifi...

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Main Authors: Zhang, Qihang, Gamekkanda, Janaka C, Pandit, Ajinkya, Tang, Wenlong, Papageorgiou, Charles, Mitchell, Chris, Yang, Yihui, Schwaerzler, Michael, Oyetunde, Tolutola, Braatz, Richard D, Myerson, Allan S, Barbastathis, George
Other Authors: Massachusetts Institute of Technology. Department of Mechanical Engineering
Format: Article
Language:English
Published: Springer Science and Business Media LLC 2023
Online Access:https://hdl.handle.net/1721.1/150777
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author Zhang, Qihang
Gamekkanda, Janaka C
Pandit, Ajinkya
Tang, Wenlong
Papageorgiou, Charles
Mitchell, Chris
Yang, Yihui
Schwaerzler, Michael
Oyetunde, Tolutola
Braatz, Richard D
Myerson, Allan S
Barbastathis, George
author2 Massachusetts Institute of Technology. Department of Mechanical Engineering
author_facet Massachusetts Institute of Technology. Department of Mechanical Engineering
Zhang, Qihang
Gamekkanda, Janaka C
Pandit, Ajinkya
Tang, Wenlong
Papageorgiou, Charles
Mitchell, Chris
Yang, Yihui
Schwaerzler, Michael
Oyetunde, Tolutola
Braatz, Richard D
Myerson, Allan S
Barbastathis, George
author_sort Zhang, Qihang
collection MIT
description <jats:title>Abstract</jats:title><jats:p>Extracting quantitative information about highly scattering surfaces from an imaging system is challenging because the phase of the scattered light undergoes multiple folds upon propagation, resulting in complex speckle patterns. One specific application is the drying of wet powders in the pharmaceutical industry, where quantifying the particle size distribution (PSD) is of particular interest. A non-invasive and real-time monitoring probe in the drying process is required, but there is no suitable candidate for this purpose. In this report, we develop a theoretical relationship from the PSD to the speckle image and describe a physics-enhanced autocorrelation-based estimator (PEACE) machine learning algorithm for speckle analysis to measure the PSD of a powder surface. This method solves both the forward and inverse problems together and enjoys increased interpretability, since the machine learning approximator is regularized by the physical law.</jats:p>
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spelling mit-1721.1/1507772023-05-20T03:24:22Z Extracting particle size distribution from laser speckle with a physics-enhanced autocorrelation-based estimator (PEACE) Zhang, Qihang Gamekkanda, Janaka C Pandit, Ajinkya Tang, Wenlong Papageorgiou, Charles Mitchell, Chris Yang, Yihui Schwaerzler, Michael Oyetunde, Tolutola Braatz, Richard D Myerson, Allan S Barbastathis, George Massachusetts Institute of Technology. Department of Mechanical Engineering <jats:title>Abstract</jats:title><jats:p>Extracting quantitative information about highly scattering surfaces from an imaging system is challenging because the phase of the scattered light undergoes multiple folds upon propagation, resulting in complex speckle patterns. One specific application is the drying of wet powders in the pharmaceutical industry, where quantifying the particle size distribution (PSD) is of particular interest. A non-invasive and real-time monitoring probe in the drying process is required, but there is no suitable candidate for this purpose. In this report, we develop a theoretical relationship from the PSD to the speckle image and describe a physics-enhanced autocorrelation-based estimator (PEACE) machine learning algorithm for speckle analysis to measure the PSD of a powder surface. This method solves both the forward and inverse problems together and enjoys increased interpretability, since the machine learning approximator is regularized by the physical law.</jats:p> 2023-05-19T13:34:24Z 2023-05-19T13:34:24Z 2023-03-01 2023-05-19T13:31:48Z Article http://purl.org/eprint/type/JournalArticle https://hdl.handle.net/1721.1/150777 Zhang, Qihang, Gamekkanda, Janaka C, Pandit, Ajinkya, Tang, Wenlong, Papageorgiou, Charles et al. 2023. "Extracting particle size distribution from laser speckle with a physics-enhanced autocorrelation-based estimator (PEACE)." Nature Communications, 14 (1). en 10.1038/s41467-023-36816-2 Nature Communications Creative Commons Attribution http://creativecommons.org/licenses/by/4.0/ application/pdf Springer Science and Business Media LLC Nature
spellingShingle Zhang, Qihang
Gamekkanda, Janaka C
Pandit, Ajinkya
Tang, Wenlong
Papageorgiou, Charles
Mitchell, Chris
Yang, Yihui
Schwaerzler, Michael
Oyetunde, Tolutola
Braatz, Richard D
Myerson, Allan S
Barbastathis, George
Extracting particle size distribution from laser speckle with a physics-enhanced autocorrelation-based estimator (PEACE)
title Extracting particle size distribution from laser speckle with a physics-enhanced autocorrelation-based estimator (PEACE)
title_full Extracting particle size distribution from laser speckle with a physics-enhanced autocorrelation-based estimator (PEACE)
title_fullStr Extracting particle size distribution from laser speckle with a physics-enhanced autocorrelation-based estimator (PEACE)
title_full_unstemmed Extracting particle size distribution from laser speckle with a physics-enhanced autocorrelation-based estimator (PEACE)
title_short Extracting particle size distribution from laser speckle with a physics-enhanced autocorrelation-based estimator (PEACE)
title_sort extracting particle size distribution from laser speckle with a physics enhanced autocorrelation based estimator peace
url https://hdl.handle.net/1721.1/150777
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