Computational Prediction of the Interaction of Ivermectin with Fibrinogen
Hypercoagulability and formation of extensive and difficult-to-lyse microclots are a hallmark of both acute COVID-19 and long COVID. Fibrinogen, when converted to fibrin, is responsible for clot formation, but abnormal structural and mechanical clot properties can lead to pathologic thrombosis. Rece...
Main Authors: | Vottero, Paola, Tavernini, Scott, Santin, Alessandro D., Scheim, David E., Tuszynski, Jack A., Aminpour, Maral |
---|---|
Format: | Article |
Published: |
Multidisciplinary Digital Publishing Institute
2023
|
Online Access: | https://hdl.handle.net/1721.1/151179 |
Similar Items
-
Computational Prediction of the Interaction of Ivermectin with Fibrinogen
by: Paola Vottero, et al.
Published: (2023-07-01) -
Omicron SARS-CoV-2 Spike-1 Protein’s Decreased Binding Affinity to α7nAChr: Implications for Autonomic Dysregulation of the Parasympathetic Nervous System and the Cholinergic Anti-Inflammatory Pathway—An In Silico Analysis
by: Domiziano Doria, et al.
Published: (2022-10-01) -
Computational Analysis and Experimental Testing of the Molecular Mode of Action of Gatastatin and Its Derivatives
by: Paola Vottero, et al.
Published: (2023-03-01) -
In Silico Analysis of the Multi-Targeted Mode of Action of Ivermectin and Related Compounds
by: Maral Aminpour, et al.
Published: (2022-03-01) -
Sialylated Glycan Bindings from SARS-CoV-2 Spike Protein to Blood and Endothelial Cells Govern the Severe Morbidities of COVID-19
by: Scheim, David E., et al.
Published: (2023)