Nuclear lamin isoforms differentially contribute to LINC complex-dependent nucleocytoskeletal coupling and whole-cell mechanics
<jats:title>Significance</jats:title> <jats:p>Interactions between the cell nucleus and cytoskeleton regulate cell mechanics and are facilitated by the interplay between the nuclear lamina and linker of nucleoskeleton and cytoskeleton (LINC) complexes. To date, the speci...
Main Authors: | Vahabikashi, Amir, Sivagurunathan, Suganya, Nicdao, Fiona Ann Sadsad, Han, Yu Long, Park, Chan Young, Kittisopikul, Mark, Wong, Xianrong, Tran, Joseph R, Gundersen, Gregg G, Reddy, Karen L, Luxton, GW Gant, Guo, Ming, Fredberg, Jeffrey J, Zheng, Yixian, Adam, Stephen A, Goldman, Robert D |
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Other Authors: | Massachusetts Institute of Technology. Department of Mechanical Engineering |
Format: | Article |
Language: | English |
Published: |
Proceedings of the National Academy of Sciences
2023
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Online Access: | https://hdl.handle.net/1721.1/152524 |
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