Stable Isotope-Assisted Untargeted Metabolomics Identifies ALDH1A1-Driven Erythronate Accumulation in Lung Cancer Cells
Using an untargeted stable isotope-assisted metabolomics approach, we identify erythronate as a metabolite that accumulates in several human cancer cell lines. Erythronate has been reported to be a detoxification product derived from off-target glycolytic metabolism. We use chemical inhibitors and g...
| Κύριοι συγγραφείς: | , , , , , , , , , , , , |
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| Άλλοι συγγραφείς: | |
| Μορφή: | Άρθρο |
| Έκδοση: |
Multidisciplinary Digital Publishing Institute
2023
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| Διαθέσιμο Online: | https://hdl.handle.net/1721.1/152540 |