Volumetric compression develops noise-driven single-cell heterogeneity

<jats:title>Significance</jats:title> <jats:p>Tumor heterogeneity is widely attributed to the imperfection of DNA replication. However, little is known about the mechanoregulation of tumor heterogeneity. Here, we report that volumetric compression that usually arises fro...

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Bibliographic Details
Main Authors: Zhao, Xing, Hu, Jiliang, Li, Yiwei, Guo, Ming
Other Authors: Massachusetts Institute of Technology. Department of Mechanical Engineering
Format: Article
Language:English
Published: Proceedings of the National Academy of Sciences 2023
Online Access:https://hdl.handle.net/1721.1/152549