Predictive Novelty Detection in Songbird Auditory Cortex
In order to make sense of complicated sensory landscapes, the brain privileges the processing of novel stimuli. Detecting novelty is therefore a fundamental problem for the brain to solve. And it turns out to be complicated, as stimuli can be completely novel, or just novel relative to certain certa...
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| Format: | Thesis |
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Massachusetts Institute of Technology
2023
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| Online Access: | https://hdl.handle.net/1721.1/152579 |
| _version_ | 1826210958837547008 |
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| author | Happ, Michael Liu |
| author2 | Fee, Michale S. |
| author_facet | Fee, Michale S. Happ, Michael Liu |
| author_sort | Happ, Michael Liu |
| collection | MIT |
| description | In order to make sense of complicated sensory landscapes, the brain privileges the processing of novel stimuli. Detecting novelty is therefore a fundamental problem for the brain to solve. And it turns out to be complicated, as stimuli can be completely novel, or just novel relative to certain certain contexts or expectations. To better understand how the brain detects both types of novelty, we studied an auditory region of the avian brain that performs both absolute and relative novelty detection. We introduce a predictive model, called the Agnotron, that is capable of performing both kinds of novelty detection with the same circuit mechanism. Armed with predictions made by the Agnotron, we perform experiments to confirm the existence of Agnotron-like circuitry in the brain. While we fail to find evidence that the various novelty signals in this brain area are produced by the same mechanism, we do find support for predictive circuitry for some novelty signals. We continue with an advanced investigation of one absolute novelty signal in particular, known as the Song-Specific Adaptation. After recapitulating classical results with state-of-the-art technology, we report novel phenomena that rule out predictive circuit mechanisms for the SSA. Taken together, our results suggest that predictive mechanisms can explain some novelty signals in the avian brain, but not the SSA, which seems to have a more simplistic feed-forward mechanism of generation. |
| first_indexed | 2024-09-23T14:58:11Z |
| format | Thesis |
| id | mit-1721.1/152579 |
| institution | Massachusetts Institute of Technology |
| last_indexed | 2024-09-23T14:58:11Z |
| publishDate | 2023 |
| publisher | Massachusetts Institute of Technology |
| record_format | dspace |
| spelling | mit-1721.1/1525792023-11-01T03:17:15Z Predictive Novelty Detection in Songbird Auditory Cortex Happ, Michael Liu Fee, Michale S. Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences In order to make sense of complicated sensory landscapes, the brain privileges the processing of novel stimuli. Detecting novelty is therefore a fundamental problem for the brain to solve. And it turns out to be complicated, as stimuli can be completely novel, or just novel relative to certain certain contexts or expectations. To better understand how the brain detects both types of novelty, we studied an auditory region of the avian brain that performs both absolute and relative novelty detection. We introduce a predictive model, called the Agnotron, that is capable of performing both kinds of novelty detection with the same circuit mechanism. Armed with predictions made by the Agnotron, we perform experiments to confirm the existence of Agnotron-like circuitry in the brain. While we fail to find evidence that the various novelty signals in this brain area are produced by the same mechanism, we do find support for predictive circuitry for some novelty signals. We continue with an advanced investigation of one absolute novelty signal in particular, known as the Song-Specific Adaptation. After recapitulating classical results with state-of-the-art technology, we report novel phenomena that rule out predictive circuit mechanisms for the SSA. Taken together, our results suggest that predictive mechanisms can explain some novelty signals in the avian brain, but not the SSA, which seems to have a more simplistic feed-forward mechanism of generation. Ph.D. 2023-10-30T20:04:23Z 2023-10-30T20:04:23Z 2023-06 2023-10-17T14:43:25.496Z Thesis https://hdl.handle.net/1721.1/152579 In Copyright - Educational Use Permitted Copyright retained by author(s) https://rightsstatements.org/page/InC-EDU/1.0/ application/pdf Massachusetts Institute of Technology |
| spellingShingle | Happ, Michael Liu Predictive Novelty Detection in Songbird Auditory Cortex |
| title | Predictive Novelty Detection in Songbird Auditory Cortex |
| title_full | Predictive Novelty Detection in Songbird Auditory Cortex |
| title_fullStr | Predictive Novelty Detection in Songbird Auditory Cortex |
| title_full_unstemmed | Predictive Novelty Detection in Songbird Auditory Cortex |
| title_short | Predictive Novelty Detection in Songbird Auditory Cortex |
| title_sort | predictive novelty detection in songbird auditory cortex |
| url | https://hdl.handle.net/1721.1/152579 |
| work_keys_str_mv | AT happmichaelliu predictivenoveltydetectioninsongbirdauditorycortex |