Design principles of 3D epigenetic memory systems

<jats:p>Cells remember their identities, in part, by using epigenetic marks—chemical modifications placed along the genome. How can mark patterns remain stable over cell generations despite their constant erosion by replication and other processes? We developed a theoretical model that reveals...

Full description

Bibliographic Details
Main Authors: Owen, Jeremy A., Osmanović, Dino, Mirny, Leonid
Other Authors: Massachusetts Institute of Technology. Department of Physics
Format: Article
Language:en_US
Published: American Association for the Advancement of Science (AAAS) 2023
Subjects:
Online Access:https://hdl.handle.net/1721.1/153004