Human nerve distribution and density around the carotid artery bifurcation
Modulation of the autonomic nervous system represents an attractive treatment target for cardiovascular diseases, including hypertension, heart failure and atrial fibrillation [1]. Stretch-sensitive baroreceptors in the carotid sinus contribute to short- and long-term blood pressure regulation. Incr...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Springer Science and Business Media LLC
2024
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| Online Access: | https://hdl.handle.net/1721.1/153635 |
| _version_ | 1826201406248321024 |
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| author | Struthoff, Helge Lauder, Lucas Federspiel, Jan M. Hohl, Mathias Böhm, Michael Tschernig, Thomas Mahfoud, Felix |
| author2 | Massachusetts Institute of Technology. Institute for Medical Engineering & Science |
| author_facet | Massachusetts Institute of Technology. Institute for Medical Engineering & Science Struthoff, Helge Lauder, Lucas Federspiel, Jan M. Hohl, Mathias Böhm, Michael Tschernig, Thomas Mahfoud, Felix |
| author_sort | Struthoff, Helge |
| collection | MIT |
| description | Modulation of the autonomic nervous system represents an attractive treatment target for cardiovascular diseases, including hypertension, heart failure and atrial fibrillation [1]. Stretch-sensitive baroreceptors in the carotid sinus contribute to short- and long-term blood pressure regulation. Increased wall strain due to high blood pressure increases the activity of arterial baroreceptors and thereby reduces sympathetic outflow and total peripheral resistance [3, 5]. Stimulation of the carotid baroreflex using electrical properties or a stent-like device is currently under clinical investigation in heart failure and hypertension [1]. Detailed knowledge about the nerves running along the carotid arteries is essential to identify attractive treatment targets and locations and to further refine existing technologies and techniques. Here, we analyzed the nerves traveling along the human carotid arteries. |
| first_indexed | 2024-09-23T11:51:25Z |
| format | Article |
| id | mit-1721.1/153635 |
| institution | Massachusetts Institute of Technology |
| language | English |
| last_indexed | 2024-09-23T11:51:25Z |
| publishDate | 2024 |
| publisher | Springer Science and Business Media LLC |
| record_format | dspace |
| spelling | mit-1721.1/1536352024-09-16T21:01:56Z Human nerve distribution and density around the carotid artery bifurcation Struthoff, Helge Lauder, Lucas Federspiel, Jan M. Hohl, Mathias Böhm, Michael Tschernig, Thomas Mahfoud, Felix Massachusetts Institute of Technology. Institute for Medical Engineering & Science Cardiology and Cardiovascular Medicine General Medicine Modulation of the autonomic nervous system represents an attractive treatment target for cardiovascular diseases, including hypertension, heart failure and atrial fibrillation [1]. Stretch-sensitive baroreceptors in the carotid sinus contribute to short- and long-term blood pressure regulation. Increased wall strain due to high blood pressure increases the activity of arterial baroreceptors and thereby reduces sympathetic outflow and total peripheral resistance [3, 5]. Stimulation of the carotid baroreflex using electrical properties or a stent-like device is currently under clinical investigation in heart failure and hypertension [1]. Detailed knowledge about the nerves running along the carotid arteries is essential to identify attractive treatment targets and locations and to further refine existing technologies and techniques. Here, we analyzed the nerves traveling along the human carotid arteries. 2024-03-04T15:16:36Z 2024-03-04T15:16:36Z 2024-02-26 2024-03-03T04:10:19Z Article http://purl.org/eprint/type/JournalArticle 1861-0684 1861-0692 https://hdl.handle.net/1721.1/153635 Struthoff, H., Lauder, L., Federspiel, J.M. et al. Human nerve distribution and density around the carotid artery bifurcation. Clin Res Cardiol (2024). PUBLISHER_CC en 10.1007/s00392-024-02419-0 Clinical Research in Cardiology Creative Commons Attribution https://creativecommons.org/licenses/by/4.0/ The Author(s) application/pdf Springer Science and Business Media LLC Springer Berlin Heidelberg |
| spellingShingle | Cardiology and Cardiovascular Medicine General Medicine Struthoff, Helge Lauder, Lucas Federspiel, Jan M. Hohl, Mathias Böhm, Michael Tschernig, Thomas Mahfoud, Felix Human nerve distribution and density around the carotid artery bifurcation |
| title | Human nerve distribution and density around the carotid artery bifurcation |
| title_full | Human nerve distribution and density around the carotid artery bifurcation |
| title_fullStr | Human nerve distribution and density around the carotid artery bifurcation |
| title_full_unstemmed | Human nerve distribution and density around the carotid artery bifurcation |
| title_short | Human nerve distribution and density around the carotid artery bifurcation |
| title_sort | human nerve distribution and density around the carotid artery bifurcation |
| topic | Cardiology and Cardiovascular Medicine General Medicine |
| url | https://hdl.handle.net/1721.1/153635 |
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