Will microfluidics enable functionally integrated biohybrid robots?
The next robotics frontier will be led by biohybrids. Capable biohybrid robots require microfluidics to sustain, improve, and scale the architectural complexity of their core ingredient: biological tissues. Advances in microfluidics have already revolutionized disease modeling and drug development,...
| Main Authors: | , , , , |
|---|---|
| Other Authors: | |
| Format: | Article |
| Language: | English |
| Published: |
Proceedings of the National Academy of Sciences
2024
|
| Subjects: | |
| Online Access: | https://hdl.handle.net/1721.1/154082 |
| _version_ | 1826211699529613312 |
|---|---|
| author | Filippi, Miriam Yasa, Oncay Kamm, Roger Dale Raman, Ritu Katzschmann, Robert K. |
| author2 | Massachusetts Institute of Technology. Department of Mechanical Engineering |
| author_facet | Massachusetts Institute of Technology. Department of Mechanical Engineering Filippi, Miriam Yasa, Oncay Kamm, Roger Dale Raman, Ritu Katzschmann, Robert K. |
| author_sort | Filippi, Miriam |
| collection | MIT |
| description | The next robotics frontier will be led by biohybrids. Capable biohybrid robots require microfluidics to sustain, improve, and scale the architectural complexity of their core ingredient: biological tissues. Advances in microfluidics have already revolutionized disease modeling and drug development, and are positioned to impact regenerative medicine but have yet to apply to biohybrids. Fusing microfluidics with living materials will improve tissue perfusion and maturation, and enable precise patterning of sensing, processing, and control elements. This perspective suggests future developments in advanced biohybrids. |
| first_indexed | 2024-09-23T15:10:07Z |
| format | Article |
| id | mit-1721.1/154082 |
| institution | Massachusetts Institute of Technology |
| language | English |
| last_indexed | 2025-02-19T04:24:21Z |
| publishDate | 2024 |
| publisher | Proceedings of the National Academy of Sciences |
| record_format | dspace |
| spelling | mit-1721.1/1540822025-01-02T04:49:10Z Will microfluidics enable functionally integrated biohybrid robots? Filippi, Miriam Yasa, Oncay Kamm, Roger Dale Raman, Ritu Katzschmann, Robert K. Massachusetts Institute of Technology. Department of Mechanical Engineering Massachusetts Institute of Technology. Department of Biological Engineering Multidisciplinary The next robotics frontier will be led by biohybrids. Capable biohybrid robots require microfluidics to sustain, improve, and scale the architectural complexity of their core ingredient: biological tissues. Advances in microfluidics have already revolutionized disease modeling and drug development, and are positioned to impact regenerative medicine but have yet to apply to biohybrids. Fusing microfluidics with living materials will improve tissue perfusion and maturation, and enable precise patterning of sensing, processing, and control elements. This perspective suggests future developments in advanced biohybrids. 2024-04-05T19:49:48Z 2024-04-05T19:49:48Z 2022-08-24 2024-04-05T19:38:46Z Article http://purl.org/eprint/type/JournalArticle 0027-8424 1091-6490 https://hdl.handle.net/1721.1/154082 Filippi, Miriam, Yasa, Oncay, Kamm, Roger Dale, Raman, Ritu and Katzschmann, Robert K. 2022. "Will microfluidics enable functionally integrated biohybrid robots?." Proceedings of the National Academy of Sciences, 119 (35). en 10.1073/pnas.2200741119 Proceedings of the National Academy of Sciences Creative Commons Attribution-NonCommercial-NoDerivs License https://creativecommons.org/licenses/by-nc-nd/4.0/ application/pdf Proceedings of the National Academy of Sciences National Academy of Sciences |
| spellingShingle | Multidisciplinary Filippi, Miriam Yasa, Oncay Kamm, Roger Dale Raman, Ritu Katzschmann, Robert K. Will microfluidics enable functionally integrated biohybrid robots? |
| title | Will microfluidics enable functionally integrated biohybrid robots? |
| title_full | Will microfluidics enable functionally integrated biohybrid robots? |
| title_fullStr | Will microfluidics enable functionally integrated biohybrid robots? |
| title_full_unstemmed | Will microfluidics enable functionally integrated biohybrid robots? |
| title_short | Will microfluidics enable functionally integrated biohybrid robots? |
| title_sort | will microfluidics enable functionally integrated biohybrid robots |
| topic | Multidisciplinary |
| url | https://hdl.handle.net/1721.1/154082 |
| work_keys_str_mv | AT filippimiriam willmicrofluidicsenablefunctionallyintegratedbiohybridrobots AT yasaoncay willmicrofluidicsenablefunctionallyintegratedbiohybridrobots AT kammrogerdale willmicrofluidicsenablefunctionallyintegratedbiohybridrobots AT ramanritu willmicrofluidicsenablefunctionallyintegratedbiohybridrobots AT katzschmannrobertk willmicrofluidicsenablefunctionallyintegratedbiohybridrobots |