Use of artificial intelligence in critical care: opportunities and obstacles

Background Perhaps nowhere else in the healthcare system than in the intensive care unit environment are the challenges to create useful models with direct time-critical clinical applications more relevant and the obstacles to achieving those goals more massive. Machine learning-bas...

Full description

Bibliographic Details
Main Authors: Pinsky, Michael R., Bedoya, Armando, Bihorac, Azra, Celi, Leo, Churpek, Matthew, Economou-Zavlanos, Nicoleta J., Elbers, Paul, Saria, Suchi, Liu, Vincent, Lyons, Patrick G., Shickel, Benjamin, Toral, Patrick, Tscholl, David, Clermont, Gilles
Format: Article
Language:English
Published: Springer Science and Business Media LLC 2024
Subjects:
Online Access:https://hdl.handle.net/1721.1/154170
_version_ 1811072961887600640
author Pinsky, Michael R.
Bedoya, Armando
Bihorac, Azra
Celi, Leo
Churpek, Matthew
Economou-Zavlanos, Nicoleta J.
Elbers, Paul
Saria, Suchi
Liu, Vincent
Lyons, Patrick G.
Shickel, Benjamin
Toral, Patrick
Tscholl, David
Clermont, Gilles
author_facet Pinsky, Michael R.
Bedoya, Armando
Bihorac, Azra
Celi, Leo
Churpek, Matthew
Economou-Zavlanos, Nicoleta J.
Elbers, Paul
Saria, Suchi
Liu, Vincent
Lyons, Patrick G.
Shickel, Benjamin
Toral, Patrick
Tscholl, David
Clermont, Gilles
author_sort Pinsky, Michael R.
collection MIT
description Background Perhaps nowhere else in the healthcare system than in the intensive care unit environment are the challenges to create useful models with direct time-critical clinical applications more relevant and the obstacles to achieving those goals more massive. Machine learning-based artificial intelligence (AI) techniques to define states and predict future events are commonplace activities of modern life. However, their penetration into acute care medicine has been slow, stuttering and uneven. Major obstacles to widespread effective application of AI approaches to the real-time care of the critically ill patient exist and need to be addressed. Main body Clinical decision support systems (CDSSs) in acute and critical care environments support clinicians, not replace them at the bedside. As will be discussed in this review, the reasons are many and include the immaturity of AI-based systems to have situational awareness, the fundamental bias in many large databases that do not reflect the target population of patient being treated making fairness an important issue to address and technical barriers to the timely access to valid data and its display in a fashion useful for clinical workflow. The inherent “black-box” nature of many predictive algorithms and CDSS makes trustworthiness and acceptance by the medical community difficult. Logistically, collating and curating in real-time multidimensional data streams of various sources needed to inform the algorithms and ultimately display relevant clinical decisions support format that adapt to individual patient responses and signatures represent the efferent limb of these systems and is often ignored during initial validation efforts. Similarly, legal and commercial barriers to the access to many existing clinical databases limit studies to address fairness and generalizability of predictive models and management tools. Conclusions AI-based CDSS are evolving and are here to stay. It is our obligation to be good shepherds of their use and further development.
first_indexed 2024-09-23T09:23:04Z
format Article
id mit-1721.1/154170
institution Massachusetts Institute of Technology
language English
last_indexed 2024-09-23T09:23:04Z
publishDate 2024
publisher Springer Science and Business Media LLC
record_format dspace
spelling mit-1721.1/1541702024-04-18T03:57:25Z Use of artificial intelligence in critical care: opportunities and obstacles Pinsky, Michael R. Bedoya, Armando Bihorac, Azra Celi, Leo Churpek, Matthew Economou-Zavlanos, Nicoleta J. Elbers, Paul Saria, Suchi Liu, Vincent Lyons, Patrick G. Shickel, Benjamin Toral, Patrick Tscholl, David Clermont, Gilles Critical Care and Intensive Care Medicine Background Perhaps nowhere else in the healthcare system than in the intensive care unit environment are the challenges to create useful models with direct time-critical clinical applications more relevant and the obstacles to achieving those goals more massive. Machine learning-based artificial intelligence (AI) techniques to define states and predict future events are commonplace activities of modern life. However, their penetration into acute care medicine has been slow, stuttering and uneven. Major obstacles to widespread effective application of AI approaches to the real-time care of the critically ill patient exist and need to be addressed. Main body Clinical decision support systems (CDSSs) in acute and critical care environments support clinicians, not replace them at the bedside. As will be discussed in this review, the reasons are many and include the immaturity of AI-based systems to have situational awareness, the fundamental bias in many large databases that do not reflect the target population of patient being treated making fairness an important issue to address and technical barriers to the timely access to valid data and its display in a fashion useful for clinical workflow. The inherent “black-box” nature of many predictive algorithms and CDSS makes trustworthiness and acceptance by the medical community difficult. Logistically, collating and curating in real-time multidimensional data streams of various sources needed to inform the algorithms and ultimately display relevant clinical decisions support format that adapt to individual patient responses and signatures represent the efferent limb of these systems and is often ignored during initial validation efforts. Similarly, legal and commercial barriers to the access to many existing clinical databases limit studies to address fairness and generalizability of predictive models and management tools. Conclusions AI-based CDSS are evolving and are here to stay. It is our obligation to be good shepherds of their use and further development. 2024-04-17T12:35:20Z 2024-04-17T12:35:20Z 2024-04-08 2024-04-14T03:12:32Z Article http://purl.org/eprint/type/JournalArticle 1364-8535 https://hdl.handle.net/1721.1/154170 Pinsky, M.R., Bedoya, A., Bihorac, A. et al. Use of artificial intelligence in critical care: opportunities and obstacles. Crit Care 28, 113 (2024). PUBLISHER_CC en 10.1186/s13054-024-04860-z Critical Care Creative Commons Attribution https://creativecommons.org/licenses/by/4.0/ The Author(s) application/pdf Springer Science and Business Media LLC BioMed Central
spellingShingle Critical Care and Intensive Care Medicine
Pinsky, Michael R.
Bedoya, Armando
Bihorac, Azra
Celi, Leo
Churpek, Matthew
Economou-Zavlanos, Nicoleta J.
Elbers, Paul
Saria, Suchi
Liu, Vincent
Lyons, Patrick G.
Shickel, Benjamin
Toral, Patrick
Tscholl, David
Clermont, Gilles
Use of artificial intelligence in critical care: opportunities and obstacles
title Use of artificial intelligence in critical care: opportunities and obstacles
title_full Use of artificial intelligence in critical care: opportunities and obstacles
title_fullStr Use of artificial intelligence in critical care: opportunities and obstacles
title_full_unstemmed Use of artificial intelligence in critical care: opportunities and obstacles
title_short Use of artificial intelligence in critical care: opportunities and obstacles
title_sort use of artificial intelligence in critical care opportunities and obstacles
topic Critical Care and Intensive Care Medicine
url https://hdl.handle.net/1721.1/154170
work_keys_str_mv AT pinskymichaelr useofartificialintelligenceincriticalcareopportunitiesandobstacles
AT bedoyaarmando useofartificialintelligenceincriticalcareopportunitiesandobstacles
AT bihoracazra useofartificialintelligenceincriticalcareopportunitiesandobstacles
AT celileo useofartificialintelligenceincriticalcareopportunitiesandobstacles
AT churpekmatthew useofartificialintelligenceincriticalcareopportunitiesandobstacles
AT economouzavlanosnicoletaj useofartificialintelligenceincriticalcareopportunitiesandobstacles
AT elberspaul useofartificialintelligenceincriticalcareopportunitiesandobstacles
AT sariasuchi useofartificialintelligenceincriticalcareopportunitiesandobstacles
AT liuvincent useofartificialintelligenceincriticalcareopportunitiesandobstacles
AT lyonspatrickg useofartificialintelligenceincriticalcareopportunitiesandobstacles
AT shickelbenjamin useofartificialintelligenceincriticalcareopportunitiesandobstacles
AT toralpatrick useofartificialintelligenceincriticalcareopportunitiesandobstacles
AT tscholldavid useofartificialintelligenceincriticalcareopportunitiesandobstacles
AT clermontgilles useofartificialintelligenceincriticalcareopportunitiesandobstacles