An immune-competent human gut microphysiological system enables inflammation-modulation by Faecalibacterium prausnitzii

Crosstalk of microbes with human gut epithelia and immune cells is crucial for gut health. However, there is no existing system for a long-term co-culture of human innate immune cells with epithelium and oxygen-intolerant commensal microbes, hindering the understanding of microbe-immune interactions...

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Bibliographic Details
Main Authors: Zhang, Jianbo, Huang, Yu-Ja, Trapecar, Martin, Wright, Charles, Schneider, Kirsten, Kemmitt, John, Hernandez-Gordillo, Victor, Yoon, Jun Young, Poyet, Mathilde, Alm, Eric J., Breault, David T., Trumper, David L., Griffith, Linda G.
Format: Article
Language:English
Published: Springer Science and Business Media LLC 2024
Online Access:https://hdl.handle.net/1721.1/154888