Oral mRNA delivery using capsule-mediated gastrointestinal tissue injections

Nucleic acids are enabling a new generation of therapeutics and vaccines to treat and prevent a range of diseases. While these therapies have typically been limited to parenteral dosing, patients and clinicians prefer oral dosage forms. Furthermore, oral delivery enables local transfection of cells...

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Dettagli Bibliografici
Autori principali: Abramson, Alex, Kirtane, Ameya R., Shi, Yunhua, Zhong, Grace, Collins, Joy E., Tamang, Siddartha, Ishida, Keiko, Hayward, Alison, Wainer, Jacob, Rajesh, Netra Unni, Lu, Xiaoya, Gao, Yuan, Karandikar, Paramesh, Tang, Chaoyang, Lopes, Aaron, Wahane, Aniket, Reker, Daniel, Frederiksen, Morten Revsgaard, Jensen, Brian, Langer, Robert, Traverso, Giovanni
Altri autori: Massachusetts Institute of Technology. Department of Chemical Engineering
Natura: Articolo
Lingua:English
Pubblicazione: Elsevier BV 2024
Accesso online:https://hdl.handle.net/1721.1/155045

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