Oral mRNA delivery using capsule-mediated gastrointestinal tissue injections

Oral mRNA delivery using capsule-mediated gastrointestinal tissue injections

Nucleic acids are enabling a new generation of therapeutics and vaccines to treat and prevent a range of diseases. While these therapies have typically been limited to parenteral dosing, patients and clinicians prefer oral dosage forms. Furthermore, oral delivery enables local transfection of cells...

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Bibliographic Details
Main Authors: Abramson, Alex, Kirtane, Ameya R., Shi, Yunhua, Zhong, Grace, Collins, Joy E., Tamang, Siddartha, Ishida, Keiko, Hayward, Alison, Wainer, Jacob, Rajesh, Netra Unni, Lu, Xiaoya, Gao, Yuan, Karandikar, Paramesh, Tang, Chaoyang, Lopes, Aaron, Wahane, Aniket, Reker, Daniel, Frederiksen, Morten Revsgaard, Jensen, Brian, Langer, Robert, Traverso, Giovanni
Other Authors: Massachusetts Institute of Technology. Department of Chemical Engineering
Format: Article
Language:English
Published: Elsevier BV 2024
Online Access:https://hdl.handle.net/1721.1/155045

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