Oral mRNA delivery using capsule-mediated gastrointestinal tissue injections
Nucleic acids are enabling a new generation of therapeutics and vaccines to treat and prevent a range of diseases. While these therapies have typically been limited to parenteral dosing, patients and clinicians prefer oral dosage forms. Furthermore, oral delivery enables local transfection of cells...
Autori principali: | Abramson, Alex, Kirtane, Ameya R., Shi, Yunhua, Zhong, Grace, Collins, Joy E., Tamang, Siddartha, Ishida, Keiko, Hayward, Alison, Wainer, Jacob, Rajesh, Netra Unni, Lu, Xiaoya, Gao, Yuan, Karandikar, Paramesh, Tang, Chaoyang, Lopes, Aaron, Wahane, Aniket, Reker, Daniel, Frederiksen, Morten Revsgaard, Jensen, Brian, Langer, Robert, Traverso, Giovanni |
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Altri autori: | Massachusetts Institute of Technology. Department of Chemical Engineering |
Natura: | Articolo |
Lingua: | English |
Pubblicazione: |
Elsevier BV
2024
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Accesso online: | https://hdl.handle.net/1721.1/155045 |
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