Human-Mouse Neural Crest Chimeras as a Novel Model for Human Melanocyte Biology in Development and Disease
Limited persistence of xenogenic cells in human-mouse interspecies chimeras is an essential obstacle to overcome for the creation of disease models which allow the study of in vivo human cells. The two main barriers to donor cell survival are (1) having the capacity to respond appropriately to the x...
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Massachusetts Institute of Technology
2024
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| Online Access: | https://hdl.handle.net/1721.1/155398 |