7.346 Virus-host Interactions in Infectious Diseases, Spring 2013
Co-evolution and adaptation between viruses and humans are often portrayed as a zero-sum biological arms race. Viruses enter host cells equipped with an array of mechanisms to evade the host defense responses and replicate. The rapid rate of mutation of viruses permits evolution of various methodolo...
| Main Authors: | , |
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| Format: | Learning Object |
| Language: | en_US |
| Published: |
2024
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| Online Access: | https://hdl.handle.net/1721.1/155679 |
| _version_ | 1811077429254422528 |
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| author | Sanyal, Sumana Ashour, Joseph |
| author_facet | Sanyal, Sumana Ashour, Joseph |
| author_sort | Sanyal, Sumana |
| collection | MIT |
| description | Co-evolution and adaptation between viruses and humans are often portrayed as a zero-sum biological arms race. Viruses enter host cells equipped with an array of mechanisms to evade the host defense responses and replicate. The rapid rate of mutation of viruses permits evolution of various methodologies for infection, which in turn drive development of non-specific but highly effective host mechanisms to restrict infection. This class will discuss the varied solutions each side has developed as a means for survival. We will use examples drawn from human disease-causing pathogens that contribute seriously to the global health burden, including HIV, influenza and dengue virus. Primary research papers will be discussed to help students learn to pose scientific questions and design and conduct experiments to answer the questions and critically interpret data. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive setting. Many instructors of the Advanced Undergraduate Seminars are postdoctoral scientists with a strong interest in teaching. |
| first_indexed | 2024-09-23T10:42:52Z |
| format | Learning Object |
| id | mit-1721.1/155679 |
| institution | Massachusetts Institute of Technology |
| language | en_US |
| last_indexed | 2024-09-23T10:42:52Z |
| publishDate | 2024 |
| record_format | dspace |
| spelling | mit-1721.1/1556792024-07-15T23:20:37Z 7.346 Virus-host Interactions in Infectious Diseases, Spring 2013 Sanyal, Sumana Ashour, Joseph virus host infection protein-protein interactions host mimicry intra-cellular trafficking host-cell machinery signaling pathways antiviral proteins HIV influenza dengue virus biotechnology vaccine development host sensors IFN production Secreted IFN filoviruses hCMV IFITM proteins Co-evolution and adaptation between viruses and humans are often portrayed as a zero-sum biological arms race. Viruses enter host cells equipped with an array of mechanisms to evade the host defense responses and replicate. The rapid rate of mutation of viruses permits evolution of various methodologies for infection, which in turn drive development of non-specific but highly effective host mechanisms to restrict infection. This class will discuss the varied solutions each side has developed as a means for survival. We will use examples drawn from human disease-causing pathogens that contribute seriously to the global health burden, including HIV, influenza and dengue virus. Primary research papers will be discussed to help students learn to pose scientific questions and design and conduct experiments to answer the questions and critically interpret data. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive setting. Many instructors of the Advanced Undergraduate Seminars are postdoctoral scientists with a strong interest in teaching. 2024-07-15T23:20:13Z 2024-07-15T23:20:13Z 2013-06 Learning Object 7.346-Spring2013 7.346 IMSCP-MD5-a657ada095e8eecf84a2ae1b66c691b9 https://hdl.handle.net/1721.1/155679 en_US Attribution-NonCommercial-NoDerivs 3.0 United States http://creativecommons.org/licenses/by-nc-nd/3.0/us/ application/zip |
| spellingShingle | virus host infection protein-protein interactions host mimicry intra-cellular trafficking host-cell machinery signaling pathways antiviral proteins HIV influenza dengue virus biotechnology vaccine development host sensors IFN production Secreted IFN filoviruses hCMV IFITM proteins Sanyal, Sumana Ashour, Joseph 7.346 Virus-host Interactions in Infectious Diseases, Spring 2013 |
| title | 7.346 Virus-host Interactions in Infectious Diseases, Spring 2013 |
| title_full | 7.346 Virus-host Interactions in Infectious Diseases, Spring 2013 |
| title_fullStr | 7.346 Virus-host Interactions in Infectious Diseases, Spring 2013 |
| title_full_unstemmed | 7.346 Virus-host Interactions in Infectious Diseases, Spring 2013 |
| title_short | 7.346 Virus-host Interactions in Infectious Diseases, Spring 2013 |
| title_sort | 7 346 virus host interactions in infectious diseases spring 2013 |
| topic | virus host infection protein-protein interactions host mimicry intra-cellular trafficking host-cell machinery signaling pathways antiviral proteins HIV influenza dengue virus biotechnology vaccine development host sensors IFN production Secreted IFN filoviruses hCMV IFITM proteins |
| url | https://hdl.handle.net/1721.1/155679 |
| work_keys_str_mv | AT sanyalsumana 7346virushostinteractionsininfectiousdiseasesspring2013 AT ashourjoseph 7346virushostinteractionsininfectiousdiseasesspring2013 |