The Pro-Apoptotic Function of CED-9 Requires a CED-9-CED-4 Interaction
Apoptosis is a fundamental, conserved process of cell death required for animal development and tissue homeostasis. In Caenorhabditis elegans apoptosis is inhibited by the BCL-2 homolog CED-9. In addition to its canonical anti-apoptotic role, CED-9 possesses an apparent proapoptotic function, becau...
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| Format: | Thesis |
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Massachusetts Institute of Technology
2024
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| Online Access: | https://hdl.handle.net/1721.1/156351 |