QuickFit: A High-Throughput RT-qPCR-Based Assay to Quantify Viral Growth and Fitness In Vitro

QuickFit: A High-Throughput RT-qPCR-Based Assay to Quantify Viral Growth and Fitness In Vitro

Quantifying viral growth rates is key to understanding evolutionary dynamics and the potential for mutants to escape antiviral drugs. Defining evolutionary escape paths and their impact on viral fitness allows for the development of drugs that are resistant to escape. In the case of HIV, combination...

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Bibliographic Details
Main Authors:	Galvez, Nicolas M. S., Sheehan, Maegan L., Lin, Allen Z., Cao, Yi, Lam, Evan C., Jackson, Abigail M., Balazs, Alejandro B.
Other Authors:	Ragon Institute of MGH, MIT and Harvard
Format:	Article
Published:	Multidisciplinary Digital Publishing Institute 2024
Online Access:	https://hdl.handle.net/1721.1/156414

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