Cognitive Effects of Simulated Galactic Cosmic Radiation Are Mediated by ApoE Status, Sex, and Environment in APP Knock-In Mice

Cognitive Effects of Simulated Galactic Cosmic Radiation Are Mediated by ApoE Status, Sex, and Environment in APP Knock-In Mice

Cosmic radiation experienced during space travel may increase the risk of cognitive impairment. While simulated galactic cosmic radiation (GCRsim) has led to memory deficits in wildtype (WT) mice, it has not been investigated whether GCRsim in combination with genetic risk factors for Alzheimer&...

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Detalhes bibliográficos
Principais autores:	Wieg, Laura, Ciola, Jason C., Wasén, Caroline C., Gaba, Fidelia, Colletti, Brianna R., Schroeder, Maren K., Hinshaw, Robert G., Ekwudo, Millicent N., Holtzman, David M., Saito, Takashi, Sasaguri, Hiroki, Saido, Takaomi C., Cox, Laura M., Lemere, Cynthia A.
Outros Autores:	Harvard University--MIT Division of Health Sciences and Technology
Formato:	Artigo
Publicado em:	Multidisciplinary Digital Publishing Institute 2024
Acesso em linha:	https://hdl.handle.net/1721.1/156736

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