Cognitive Effects of Simulated Galactic Cosmic Radiation Are Mediated by ApoE Status, Sex, and Environment in APP Knock-In Mice
Cosmic radiation experienced during space travel may increase the risk of cognitive impairment. While simulated galactic cosmic radiation (GCRsim) has led to memory deficits in wildtype (WT) mice, it has not been investigated whether GCRsim in combination with genetic risk factors for Alzheimer&...
Main Authors: | Wieg, Laura, Ciola, Jason C., Wasén, Caroline C., Gaba, Fidelia, Colletti, Brianna R., Schroeder, Maren K., Hinshaw, Robert G., Ekwudo, Millicent N., Holtzman, David M., Saito, Takashi, Sasaguri, Hiroki, Saido, Takaomi C., Cox, Laura M., Lemere, Cynthia A. |
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Format: | Article |
Published: |
Multidisciplinary Digital Publishing Institute
2024
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Online Access: | https://hdl.handle.net/1721.1/156736 |
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