CRISPR-enabled point-of-care genotyping for APOL1 genetic risk assessment

CRISPR-enabled point-of-care genotyping for APOL1 genetic risk assessment

Detecting genetic variants enables risk factor identification, disease screening, and initiation of preventative therapeutics. However, current methods, relying on hybridization or sequencing, are unsuitable for point-of-care settings. In contrast, CRISPR-based-diagnostics offer high sensitivity and...

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Bibliographic Details
Main Authors: Greensmith, Robert, Lape, Isadora T., Riella, Cristian V., Schubert, Alexander J., Metzger, Jakob J., Dighe, Anand S., Tan, Xiao, Hemmer, Bernhard, Rau, Josefine, Wendlinger, Sarah, Diederich, Nora, Schütz, Anja, Riella, Leonardo V.
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science
Format: Article
Language:English
Published: Nature Publishing Group UK 2024
Online Access:https://hdl.handle.net/1721.1/156882

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