Experimental and Computational Advancements in Peptidomimetic Ligand Discovery
The usage of peptides as therapeutics is a growing area of interest within the pharmaceutical industry for the facilitation of protein-protein interactions (PPIs). Peptides inhabit a unique therapeutic space because of their high levels of chemical customization balanced with their potential for hig...
Main Author: | Lee, Michael Alan |
---|---|
Other Authors: | Pentelute, Bradley L. |
Format: | Thesis |
Published: |
Massachusetts Institute of Technology
2024
|
Online Access: | https://hdl.handle.net/1721.1/157078 https://orcid.org/0000-0001-6321-0994 |
Similar Items
-
Discovery of novel ligands using phage display
by: Nur Azri Muhamad Azan
Published: (2016) -
Discovery of a small-molecule inhibitor of STAT3 by ligand-based pharmacophore screening
by: Leung, Ka-Ho, et al.
Published: (2016) -
Computer-aided multi-objective optimization in small molecule discovery
by: Fromer, Jenna C, et al.
Published: (2025) -
Computational discovery of microstructured composites with optimal stiffness-toughness trade-offs
by: Li, Beichen, et al.
Published: (2024) -
Dry-casting : computer simulation, sensitivity analysis, experimental and phenomenological model studies
by: Krantz, William B., et al.
Published: (2013)