Engineering Medical Devices to Improve Oral Delivery of Biopharmaceuticals
The dynamic mechanics of the gastrointestinal (GI) tract, including gut contractions, variable pH, and degradative enzymes, significantly challenge the development of oral delivery systems for biologic drugs by compromising their reliable delivery and therapeutic efficacy. While recent advances in o...
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Massachusetts Institute of Technology
2024
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| Online Access: | https://hdl.handle.net/1721.1/157196 https://orcid.org/0000-0003-1016-647X |