Inhibitory Potential of the Truncated Isoforms on Glutamate Transporter Oligomerization Identified by Computational Analysis of Gene-Centric Isoform Maps

Objective Glutamate transporters play a key role in central nervous system physiology by maintaining excitatory neurotransmitter homeostasis. Biological assemblies of the transporters, consisting of cyclic homotrimers, emerge as a crucial aspect of glutamate transporter modulation. Hence targeting h...

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Bibliographic Details
Main Authors: Karagöl, Alper, Karagöl, Taner, Li, Mengke, Zhang, Shuguang
Other Authors: Massachusetts Institute of Technology. Media Laboratory
Format: Article
Language:English
Published: Springer US 2024
Online Access:https://hdl.handle.net/1721.1/157515