Inhibitory Potential of the Truncated Isoforms on Glutamate Transporter Oligomerization Identified by Computational Analysis of Gene-Centric Isoform Maps
Objective Glutamate transporters play a key role in central nervous system physiology by maintaining excitatory neurotransmitter homeostasis. Biological assemblies of the transporters, consisting of cyclic homotrimers, emerge as a crucial aspect of glutamate transporter modulation. Hence targeting h...
Main Authors: | Karagöl, Alper, Karagöl, Taner, Li, Mengke, Zhang, Shuguang |
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Other Authors: | Massachusetts Institute of Technology. Media Laboratory |
Format: | Article |
Language: | English |
Published: |
Springer US
2024
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Online Access: | https://hdl.handle.net/1721.1/157515 |
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