Renewing Our Focus on Vulnerable Populations Among People Living with HIV
The global HIV landscape has changed over the past few decades, with great milestones achieved in both HIV treatment and prevention. Access to lifesaving antiretroviral therapy (ART) has markedly expanded, with a total of 30.7 million (27 million–31.9 million) out of 39.9 million (36.1 million–44.6...
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| Format: | Article |
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Multidisciplinary Digital Publishing Institute
2024
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| Online Access: | https://hdl.handle.net/1721.1/157688 |
| _version_ | 1824458049041989632 |
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| author | Ayieko, James Thorp, Marguerite Ghebremichael, Musie |
| author2 | Ragon Institute of MGH, MIT and Harvard |
| author_facet | Ragon Institute of MGH, MIT and Harvard Ayieko, James Thorp, Marguerite Ghebremichael, Musie |
| author_sort | Ayieko, James |
| collection | MIT |
| description | The global HIV landscape has changed over the past few decades, with great milestones achieved in both HIV treatment and prevention. Access to lifesaving antiretroviral therapy (ART) has markedly expanded, with a total of 30.7 million (27 million–31.9 million) out of 39.9 million (36.1 million–44.6 million) people living with HIV accessing the medication in 2023 [1]. Continued expansion of access to, initiation of, and adherence to treatment is crucial in achieving control of the HIV pandemic, given the strong evidence that treatment is prevention [2]. Despite these marked advances, 28% of people living with HIV (PLHIV) are reported to be virally unsuppressed [1]. Viral non-suppression is associated with increased risk of progression to AIDS and portends poor outcomes for PLHIV [3,4]. Additionally, viral non-suppression increases the risk of onward transmission of HIV, reversing the gains made in combating the pandemic [3]. The risk of viral non-suppression is greater in certain groups. This Special Issue focuses on exploring HIV support, care, and treatment for vulnerable populations, or those at elevated risk of viral non-suppression and poor health outcomes.
We solicited articles on this topic and received submissions from diverse settings and authors of different backgrounds and training. The interest and importance of this topic are revealed in the diversity of articles that were submitted and the disciplines that showed interest. This Special Issue contains ten articles that advance our understanding of vulnerable populations, challenge the current thinking about vulnerable populations, and propose bold interventions to address the barriers to HIV care engagement throughout the cascade.
The articles in this Special Issue bring to the fore three critical questions about vulnerable groups: What makes one vulnerable? What are the threats to care engagement for vulnerable people? And what health care system changes are needed to accommodate vulnerable people? These questions must be addressed to improve outcomes among vulnerable groups, especially to design interventions that address their concerns. |
| first_indexed | 2025-02-19T04:19:42Z |
| format | Article |
| id | mit-1721.1/157688 |
| institution | Massachusetts Institute of Technology |
| last_indexed | 2025-02-19T04:19:42Z |
| publishDate | 2024 |
| publisher | Multidisciplinary Digital Publishing Institute |
| record_format | dspace |
| spelling | mit-1721.1/1576882024-12-21T06:04:58Z Renewing Our Focus on Vulnerable Populations Among People Living with HIV Ayieko, James Thorp, Marguerite Ghebremichael, Musie Ragon Institute of MGH, MIT and Harvard The global HIV landscape has changed over the past few decades, with great milestones achieved in both HIV treatment and prevention. Access to lifesaving antiretroviral therapy (ART) has markedly expanded, with a total of 30.7 million (27 million–31.9 million) out of 39.9 million (36.1 million–44.6 million) people living with HIV accessing the medication in 2023 [1]. Continued expansion of access to, initiation of, and adherence to treatment is crucial in achieving control of the HIV pandemic, given the strong evidence that treatment is prevention [2]. Despite these marked advances, 28% of people living with HIV (PLHIV) are reported to be virally unsuppressed [1]. Viral non-suppression is associated with increased risk of progression to AIDS and portends poor outcomes for PLHIV [3,4]. Additionally, viral non-suppression increases the risk of onward transmission of HIV, reversing the gains made in combating the pandemic [3]. The risk of viral non-suppression is greater in certain groups. This Special Issue focuses on exploring HIV support, care, and treatment for vulnerable populations, or those at elevated risk of viral non-suppression and poor health outcomes. We solicited articles on this topic and received submissions from diverse settings and authors of different backgrounds and training. The interest and importance of this topic are revealed in the diversity of articles that were submitted and the disciplines that showed interest. This Special Issue contains ten articles that advance our understanding of vulnerable populations, challenge the current thinking about vulnerable populations, and propose bold interventions to address the barriers to HIV care engagement throughout the cascade. The articles in this Special Issue bring to the fore three critical questions about vulnerable groups: What makes one vulnerable? What are the threats to care engagement for vulnerable people? And what health care system changes are needed to accommodate vulnerable people? These questions must be addressed to improve outcomes among vulnerable groups, especially to design interventions that address their concerns. 2024-11-27T16:54:32Z 2024-11-27T16:54:32Z 2024-11-14 2024-11-26T17:42:57Z Article http://purl.org/eprint/type/JournalArticle https://hdl.handle.net/1721.1/157688 Ayieko, J.; Thorp, M.; Ghebremichael, M. Renewing Our Focus on Vulnerable Populations Among People Living with HIV. Trop. Med. Infect. Dis. 2024, 9, 278. PUBLISHER_CC http://dx.doi.org/10.3390/tropicalmed9110278 Tropical Medicine and Infectious Disease Creative Commons Attribution https://creativecommons.org/licenses/by/4.0/ application/pdf Multidisciplinary Digital Publishing Institute Multidisciplinary Digital Publishing Institute |
| spellingShingle | Ayieko, James Thorp, Marguerite Ghebremichael, Musie Renewing Our Focus on Vulnerable Populations Among People Living with HIV |
| title | Renewing Our Focus on Vulnerable Populations Among People Living with HIV |
| title_full | Renewing Our Focus on Vulnerable Populations Among People Living with HIV |
| title_fullStr | Renewing Our Focus on Vulnerable Populations Among People Living with HIV |
| title_full_unstemmed | Renewing Our Focus on Vulnerable Populations Among People Living with HIV |
| title_short | Renewing Our Focus on Vulnerable Populations Among People Living with HIV |
| title_sort | renewing our focus on vulnerable populations among people living with hiv |
| url | https://hdl.handle.net/1721.1/157688 |
| work_keys_str_mv | AT ayiekojames renewingourfocusonvulnerablepopulationsamongpeoplelivingwithhiv AT thorpmarguerite renewingourfocusonvulnerablepopulationsamongpeoplelivingwithhiv AT ghebremichaelmusie renewingourfocusonvulnerablepopulationsamongpeoplelivingwithhiv |