Piezoelectric single crystal based one-dimensional phased array for breast tissue imaging
Ultrasound is widely used in clinical practice because it is safe, non-invasive, non-ionizing, low-cost, and provides real-time imaging, monitoring, and therapy. However, conventional ultrasound probes are rigid, pressure-required, and operator-dependent. Replacing rigid transducers with conformable...
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| Format: | Thesis |
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Massachusetts Institute of Technology
2024
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| Online Access: | https://hdl.handle.net/1721.1/157727 |
| _version_ | 1824458331635318784 |
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| author | Du, Wenya |
| author2 | Dagdeviren, Canan |
| author_facet | Dagdeviren, Canan Du, Wenya |
| author_sort | Du, Wenya |
| collection | MIT |
| description | Ultrasound is widely used in clinical practice because it is safe, non-invasive, non-ionizing, low-cost, and provides real-time imaging, monitoring, and therapy. However, conventional ultrasound probes are rigid, pressure-required, and operator-dependent. Replacing rigid transducers with conformable ultrasound transducer arrays can allow image acquisition on curved body parts, improve image quality, and enable functions such as long-term monitoring. In this thesis, I propose a conformable ultrasound breast patch (cUSBr-Patch) consisting of a one-dimensional (1D) phased array and a nature-inspired patch design, which offers large-area, deep tissue scanning and multi-angle, repeatable breast imaging while avoiding the drawbacks of conventional ultrasound imaging technologies. I used a Yb/Bi-doped PIN-PMN-PT single crystal as the active element due to its superior piezoelectric properties (d33 = 2,800 pC/N, εr = 7,000, k33 = 0.93). I then fabricated a 1D phased array transducer consisting of 64 elements with an operational frequency of 7.0 MHz. The 1D array exhibits promising acoustic performance with i) a maximum imaging depth of 80 mm, ii) contrast sensitivity of 3 dB, iii) axial/lateral resolutions of 0.25/1.0 mm at 30 mm depth, and iv) a larger field of view than the commercial handheld linear probe at depths of approximately 30 mm or deeper, indicating a potential reliable capability to detect early-stage breast tumors. Beyond this, comprehensive in vitro experimental studies establish that the cUSBr-Patch can provide accurate and reproducible imaging of different phantoms. The clinical trials reveal that the patch exhibits a sufficient contrast resolution (~3 dB) and axial/lateral resolutions of 0.25/1.0 mm at 30 mm depth, allowing the observation of small cysts (~ 0.3 cm) in the breast. This research develops a first-of-its-kind ultrasound technology for breast tissue scanning and imaging which offers a non-invasive method for tracking real-time dynamic changes of soft tissue. |
| first_indexed | 2025-02-19T04:24:12Z |
| format | Thesis |
| id | mit-1721.1/157727 |
| institution | Massachusetts Institute of Technology |
| last_indexed | 2025-02-19T04:24:12Z |
| publishDate | 2024 |
| publisher | Massachusetts Institute of Technology |
| record_format | dspace |
| spelling | mit-1721.1/1577272024-12-03T03:14:20Z Piezoelectric single crystal based one-dimensional phased array for breast tissue imaging Du, Wenya Dagdeviren, Canan Program in Media Arts and Sciences (Massachusetts Institute of Technology) Ultrasound is widely used in clinical practice because it is safe, non-invasive, non-ionizing, low-cost, and provides real-time imaging, monitoring, and therapy. However, conventional ultrasound probes are rigid, pressure-required, and operator-dependent. Replacing rigid transducers with conformable ultrasound transducer arrays can allow image acquisition on curved body parts, improve image quality, and enable functions such as long-term monitoring. In this thesis, I propose a conformable ultrasound breast patch (cUSBr-Patch) consisting of a one-dimensional (1D) phased array and a nature-inspired patch design, which offers large-area, deep tissue scanning and multi-angle, repeatable breast imaging while avoiding the drawbacks of conventional ultrasound imaging technologies. I used a Yb/Bi-doped PIN-PMN-PT single crystal as the active element due to its superior piezoelectric properties (d33 = 2,800 pC/N, εr = 7,000, k33 = 0.93). I then fabricated a 1D phased array transducer consisting of 64 elements with an operational frequency of 7.0 MHz. The 1D array exhibits promising acoustic performance with i) a maximum imaging depth of 80 mm, ii) contrast sensitivity of 3 dB, iii) axial/lateral resolutions of 0.25/1.0 mm at 30 mm depth, and iv) a larger field of view than the commercial handheld linear probe at depths of approximately 30 mm or deeper, indicating a potential reliable capability to detect early-stage breast tumors. Beyond this, comprehensive in vitro experimental studies establish that the cUSBr-Patch can provide accurate and reproducible imaging of different phantoms. The clinical trials reveal that the patch exhibits a sufficient contrast resolution (~3 dB) and axial/lateral resolutions of 0.25/1.0 mm at 30 mm depth, allowing the observation of small cysts (~ 0.3 cm) in the breast. This research develops a first-of-its-kind ultrasound technology for breast tissue scanning and imaging which offers a non-invasive method for tracking real-time dynamic changes of soft tissue. S.M. 2024-12-02T21:15:24Z 2024-12-02T21:15:24Z 2024-09 2024-11-19T19:12:29.227Z Thesis https://hdl.handle.net/1721.1/157727 In Copyright - Educational Use Permitted Copyright retained by author(s) https://rightsstatements.org/page/InC-EDU/1.0/ application/pdf Massachusetts Institute of Technology |
| spellingShingle | Du, Wenya Piezoelectric single crystal based one-dimensional phased array for breast tissue imaging |
| title | Piezoelectric single crystal based one-dimensional phased array for breast tissue imaging |
| title_full | Piezoelectric single crystal based one-dimensional phased array for breast tissue imaging |
| title_fullStr | Piezoelectric single crystal based one-dimensional phased array for breast tissue imaging |
| title_full_unstemmed | Piezoelectric single crystal based one-dimensional phased array for breast tissue imaging |
| title_short | Piezoelectric single crystal based one-dimensional phased array for breast tissue imaging |
| title_sort | piezoelectric single crystal based one dimensional phased array for breast tissue imaging |
| url | https://hdl.handle.net/1721.1/157727 |
| work_keys_str_mv | AT duwenya piezoelectricsinglecrystalbasedonedimensionalphasedarrayforbreasttissueimaging |