Echocardiogram Vector Embeddings Via R3D Transformer for the Advancement of Automated Echocardiography

BACKGROUND: Ejection fraction (EF) estimation informs patient plans in the ICU, and low EF can indicate ventricular systolic dysfunction, which increases the risk of adverse events including heart failure. Automated echocardiography models are an attractive solution for high-variance human EF estima...

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Main Authors: Chung, Daniel J, Lee, Somin Mindy, Kaker, Vasu, Zhao, Yongyi, Bin, Irbaz, Perera, Sudheesha, Sasankan, Prabhu, Tang, George, Kazzi, Brigitte, Kuo, Po-Chih, Celi, Leo A, Kpodonu, Jacques
Other Authors: Sloan School of Management
Format: Article
Language:English
Published: Elsevier BV 2025
Online Access:https://hdl.handle.net/1721.1/158123
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author Chung, Daniel J
Lee, Somin Mindy
Kaker, Vasu
Zhao, Yongyi
Bin, Irbaz
Perera, Sudheesha
Sasankan, Prabhu
Tang, George
Kazzi, Brigitte
Kuo, Po-Chih
Celi, Leo A
Kpodonu, Jacques
author2 Sloan School of Management
author_facet Sloan School of Management
Chung, Daniel J
Lee, Somin Mindy
Kaker, Vasu
Zhao, Yongyi
Bin, Irbaz
Perera, Sudheesha
Sasankan, Prabhu
Tang, George
Kazzi, Brigitte
Kuo, Po-Chih
Celi, Leo A
Kpodonu, Jacques
author_sort Chung, Daniel J
collection MIT
description BACKGROUND: Ejection fraction (EF) estimation informs patient plans in the ICU, and low EF can indicate ventricular systolic dysfunction, which increases the risk of adverse events including heart failure. Automated echocardiography models are an attractive solution for high-variance human EF estimation, and key to this goal are echocardiogram vector embeddings, which are a critical resource for computational researchers. OBJECTIVES: The authors aimed to extract the vector embeddings from each echocardiogram in the EchoNet dataset using a classifier trained to classify EF as healthy (>50%) or unhealthy (<= 50%) to create an embeddings dataset for computational researchers. METHODS: We repurposed an R3D transformer to classify whether patient EF is below or above 50%. Training, validation, and testing were done on the EchoNet dataset of 10,030 echocardiograms, and the resulting model generated embeddings for each of these videos. RESULTS: We extracted 400-dimensional vector embeddings for each of the 10,030 EchoNet echocardiograms using the trained R3D model, which achieved a test AUC of 0.916 and 87.5% accuracy, approaching the performance of comparable studies. CONCLUSIONS: We present 10,030 vector embeddings learned by this model as a resource to the cardiology research community, as well as the trained model itself. These vectors enable algorithmic improvements and multimodal applications within automated echocardiography, benefitting the research community and those with ventricular systolic dysfunction (https://github.com/Team-Echo-MIT/r3d-v0-embeddings).
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spelling mit-1721.1/1581232025-01-28T21:32:22Z Echocardiogram Vector Embeddings Via R3D Transformer for the Advancement of Automated Echocardiography Chung, Daniel J Lee, Somin Mindy Kaker, Vasu Zhao, Yongyi Bin, Irbaz Perera, Sudheesha Sasankan, Prabhu Tang, George Kazzi, Brigitte Kuo, Po-Chih Celi, Leo A Kpodonu, Jacques Sloan School of Management Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science Harvard--MIT Program in Health Sciences and Technology. Laboratory for Computational Physiology BACKGROUND: Ejection fraction (EF) estimation informs patient plans in the ICU, and low EF can indicate ventricular systolic dysfunction, which increases the risk of adverse events including heart failure. Automated echocardiography models are an attractive solution for high-variance human EF estimation, and key to this goal are echocardiogram vector embeddings, which are a critical resource for computational researchers. OBJECTIVES: The authors aimed to extract the vector embeddings from each echocardiogram in the EchoNet dataset using a classifier trained to classify EF as healthy (>50%) or unhealthy (<= 50%) to create an embeddings dataset for computational researchers. METHODS: We repurposed an R3D transformer to classify whether patient EF is below or above 50%. Training, validation, and testing were done on the EchoNet dataset of 10,030 echocardiograms, and the resulting model generated embeddings for each of these videos. RESULTS: We extracted 400-dimensional vector embeddings for each of the 10,030 EchoNet echocardiograms using the trained R3D model, which achieved a test AUC of 0.916 and 87.5% accuracy, approaching the performance of comparable studies. CONCLUSIONS: We present 10,030 vector embeddings learned by this model as a resource to the cardiology research community, as well as the trained model itself. These vectors enable algorithmic improvements and multimodal applications within automated echocardiography, benefitting the research community and those with ventricular systolic dysfunction (https://github.com/Team-Echo-MIT/r3d-v0-embeddings). 2025-01-28T21:32:20Z 2025-01-28T21:32:20Z 2024-09 2025-01-28T21:24:44Z Article http://purl.org/eprint/type/JournalArticle https://hdl.handle.net/1721.1/158123 Chung, Daniel J, Lee, Somin Mindy, Kaker, Vasu, Zhao, Yongyi, Bin, Irbaz et al. 2024. "Echocardiogram Vector Embeddings Via R3D Transformer for the Advancement of Automated Echocardiography." JACC: Advances, 3 (9). en 10.1016/j.jacadv.2024.101196 JACC: Advances Creative Commons Attribution-NonCommercial-NoDerivs License https://creativecommons.org/licenses/by-nc-nd/4.0/ application/pdf Elsevier BV Elsevier BV
spellingShingle Chung, Daniel J
Lee, Somin Mindy
Kaker, Vasu
Zhao, Yongyi
Bin, Irbaz
Perera, Sudheesha
Sasankan, Prabhu
Tang, George
Kazzi, Brigitte
Kuo, Po-Chih
Celi, Leo A
Kpodonu, Jacques
Echocardiogram Vector Embeddings Via R3D Transformer for the Advancement of Automated Echocardiography
title Echocardiogram Vector Embeddings Via R3D Transformer for the Advancement of Automated Echocardiography
title_full Echocardiogram Vector Embeddings Via R3D Transformer for the Advancement of Automated Echocardiography
title_fullStr Echocardiogram Vector Embeddings Via R3D Transformer for the Advancement of Automated Echocardiography
title_full_unstemmed Echocardiogram Vector Embeddings Via R3D Transformer for the Advancement of Automated Echocardiography
title_short Echocardiogram Vector Embeddings Via R3D Transformer for the Advancement of Automated Echocardiography
title_sort echocardiogram vector embeddings via r3d transformer for the advancement of automated echocardiography
url https://hdl.handle.net/1721.1/158123
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