Uniform volumetric single-cell processing for organ-scale molecular phenotyping

Uniform volumetric single-cell processing for organ-scale molecular phenotyping

Extending single-cell analysis to intact tissues while maintaining organ-scale spatial information poses a major challenge due to unequal chemical processing of densely packed cells. Here we introduce Continuous Redispersion of Volumetric Equilibrium (CuRVE) in nanoporous matrices, a framework to ad...

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Bibliographic Details
Main Authors: Yun, Dae Hee, Park, Young-Gyun, Cho, Jae Hun, Kamentsky, Lee, Evans, Nicholas B, DiNapoli, Nicholas, Xie, Katherine, Choi, Seo Woo, Albanese, Alexandre, Tian, Yuxuan, Sohn, Chang Ho, Zhang, Qiangge, Kim, Minyoung E, Swaney, Justin, Guan, Webster, Park, Juhyuk, Drummond, Gabi, Choi, Heejin, Ruelas, Luzdary, Feng, Guoping, Chung, Kwanghun
Other Authors: Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences
Format: Article
Language:English
Published: Springer Science and Business Media LLC 2025
Online Access:https://hdl.handle.net/1721.1/158176

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