Multiscale topological analysis of kinetoplast DNA <i>via</i> high-resolution AFM

Multiscale topological analysis of kinetoplast DNA <i>via</i> high-resolution AFM

Kinetoplast DNA is a complex nanoscale network, naturally assembled from thousands of interconnected DNA circles within the mitochondrion of certain parasites. Despite the relevance of this molecule to parasitology and the recent discovery of tuneable mechanics, its topology remains highly contested...

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Bibliographic Details
Main Authors:	Diggines, Bradley, Whittle, Sylvia, Yadav, Indresh, Holmes, Elizabeth P, Rollins, Daniel E, Catley, Thomas E, Doyle, Patrick S, Pyne, Alice LB
Other Authors:	Massachusetts Institute of Technology. Department of Chemical Engineering
Format:	Article
Language:	English
Published:	Royal Society of Chemistry 2025
Online Access:	https://hdl.handle.net/1721.1/158255

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