X-Mapper: fast and accurate sequence alignment via gapped x-mers
Sequence alignment is foundational to many bioinformatic analyses. Many aligners start by splitting sequences into contiguous, fixed-length seeds, called k-mers. Alignment is faster with longer, unique seeds, but more accurate with shorter seeds avoiding mutations. Here, we introduce X-Mapper, aimin...
Main Authors: | Gaston, Jeffry M., Alm, Eric J., Zhang, An-Ni |
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Other Authors: | Massachusetts Institute of Technology. Department of Biological Engineering |
Format: | Article |
Language: | English |
Published: |
BioMed Central
2025
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Online Access: | https://hdl.handle.net/1721.1/158285 |
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