Network tools forthe analysis and prediction of protein-protein interactions
Thesis (M. Eng.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2004.
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| Format: | Thesis |
| Language: | eng |
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Massachusetts Institute of Technology
2005
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| Online Access: | http://hdl.handle.net/1721.1/17999 |
| _version_ | 1826217269812789248 |
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| author | Weston, Kevin T. (Kevin Thomas), 1981- |
| author2 | Amy E. Keating. |
| author_facet | Amy E. Keating. Weston, Kevin T. (Kevin Thomas), 1981- |
| author_sort | Weston, Kevin T. (Kevin Thomas), 1981- |
| collection | MIT |
| description | Thesis (M. Eng.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2004. |
| first_indexed | 2024-09-23T17:00:42Z |
| format | Thesis |
| id | mit-1721.1/17999 |
| institution | Massachusetts Institute of Technology |
| language | eng |
| last_indexed | 2024-09-23T17:00:42Z |
| publishDate | 2005 |
| publisher | Massachusetts Institute of Technology |
| record_format | dspace |
| spelling | mit-1721.1/179992019-04-11T13:28:38Z Network tools forthe analysis and prediction of protein-protein interactions Weston, Kevin T. (Kevin Thomas), 1981- Amy E. Keating. Massachusetts Institute of Technology. Dept. of Electrical Engineering and Computer Science. Massachusetts Institute of Technology. Dept. of Electrical Engineering and Computer Science. Electrical Engineering and Computer Science. Thesis (M. Eng.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2004. Includes bibliographical references (p. 139-143). In this thesis, we present two computational platforms for future biological research. The first, FNAC, is a flexible programmatic Framework for Network Analysis and Comparison that simplifies many common operations on biological networks. As a demonstration of FNAC, we investigate the properties of several prominent protein function and protein-protein interaction networks. In doing so, we uncover evidence suggesting that a recently-developed technique for annotating proteins may also have substantial value in the computational prediction of protein-protein interactions. Our second computational platform, the Coiled-Coil Database (CCDB), serves as a central and easily queryable repository for information about the coiled coil protein structural motif in a variety of organisms. by Kevin T. Weston, Jr. M.Eng. 2005-06-02T19:34:15Z 2005-06-02T19:34:15Z 2004 2004 Thesis http://hdl.handle.net/1721.1/17999 57203935 eng M.I.T. theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. See provided URL for inquiries about permission. http://dspace.mit.edu/handle/1721.1/7582 143 p. 6090612 bytes 6109727 bytes application/pdf application/pdf application/pdf Massachusetts Institute of Technology |
| spellingShingle | Electrical Engineering and Computer Science. Weston, Kevin T. (Kevin Thomas), 1981- Network tools forthe analysis and prediction of protein-protein interactions |
| title | Network tools forthe analysis and prediction of protein-protein interactions |
| title_full | Network tools forthe analysis and prediction of protein-protein interactions |
| title_fullStr | Network tools forthe analysis and prediction of protein-protein interactions |
| title_full_unstemmed | Network tools forthe analysis and prediction of protein-protein interactions |
| title_short | Network tools forthe analysis and prediction of protein-protein interactions |
| title_sort | network tools forthe analysis and prediction of protein protein interactions |
| topic | Electrical Engineering and Computer Science. |
| url | http://hdl.handle.net/1721.1/17999 |
| work_keys_str_mv | AT westonkevintkevinthomas1981 networktoolsfortheanalysisandpredictionofproteinproteininteractions |