Investigation of the role of IQGAP1 in metastasis

Investigation of the role of IQGAP1 in metastasis

Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Biology, 2004.

Bibliographic Details
Main Author:	Frew, Sarah Elizabeth Ann, 1976-
Other Authors:	Richard O. Hynes.
Format:	Thesis
Language:	en_US
Published:	Massachusetts Institute of Technology 2005
Subjects:	Biology.
Online Access:	http://hdl.handle.net/1721.1/27045

Similar Items

The Antithetic Roles of IQGAP2 and IQGAP3 in Cancers
by: Fei Song, et al.
Published: (2023-02-01)

The scaffold protein IQGAP1 is crucial for extravasation and metastasis
by: Hebert, Jess D, et al.
Published: (2021)

Role of IQGAP1 in Carcinogenesis
by: Tao Wei, et al.
Published: (2021-08-01)

IQGAP1 and IQGAP2 are Reciprocally Altered in Hepatocellular Carcinoma
by: Odze Robert D, et al.
Published: (2010-10-01)

Role of IQGAP3 in metastasis and epithelial–mesenchymal transition in human hepatocellular carcinoma
by: Yongjie Shi, et al.
Published: (2017-08-01)

Downregulation of IQGAP2 Correlates with Prostate Cancer Recurrence and Metastasis
by: Yanyun Xie, et al.
Published: (2019-02-01)

Targeting ARF1-IQGAP1 interaction to suppress colorectal cancer metastasis and vemurafenib resistance
by: Hui-Fang Hu, et al.
Published: (2023-09-01)

Unraveling the mechanisms and evolution of a two-domain module in IQGAP proteins for controlling eukaryotic cytokinesis
by: Kangji Wang, et al.
Published: (2023-12-01)

Role of IQGAP1 in Papillomavirus-Associated Head and Neck Tumorigenesis
by: Tao Wei, et al.
Published: (2021-05-01)

Oncofetal protein IGF2BP1 regulates IQGAP3 expression to maintain stem cell potential in cancer
by: Khine Myint, et al.
Published: (2022-10-01)

IQGAP1 is an oncogenic target in canine melanoma.
by: Becky H Lee, et al.
Published: (2017-01-01)

IQGAP3 promotes EGFR-ERK signaling and the growth and metastasis of lung cancer cells.
by: Ying Yang, et al.
Published: (2014-01-01)

Reduced expression of IQGAP2 and higher expression of IQGAP3 correlates with poor prognosis in cancers.
by: Dinesh Kumar, et al.
Published: (2017-01-01)

Regulation of spine density and morphology by IQGAP1 protein domains.
by: Ignacio Jausoro, et al.
Published: (2013-01-01)

A role for the Spemann organizer gene, Goosecoid, in tumor metastasis
by: Hartwell, Kimberly A. (Kimberly Ann)
Published: (2007)

Hax1 regulate focal adhesion dynamics through IQGAP1
by: Xinyi Ren, et al.
Published: (2023-07-01)

IQGAP1 and NWASP promote human cancer cell dissemination and metastasis by regulating β1-integrin via FAK and MRTF/SRF
by: Camilla Cerutti, et al.
Published: (2024-04-01)

Selectivity Determinants of RHO GTPase Binding to IQGAPs
by: Niloufar Mosaddeghzadeh, et al.
Published: (2021-11-01)

Role of IQGAP1-Estrogen Receptor-AMPK Axis in the Sex Differences of Type 2 Diabetes
by: Rawan Moussa, et al.
Published: (2023-12-01)

IQGAP1 is a novel CXCR2-interacting protein and essential component of the "chemosynapse".
by: Nicole F Neel, et al.
Published: (2011-01-01)

Characterization of the Novel IQGAP1-Adrenergic Receptor Pathway in Lung Cancer
by: Omar Abdul-Aziz
Published: (2023-05-01)

IQGAP1 Negatively Regulates HIV-1 Gag Trafficking and Virion Production
by: Yosef Sabo, et al.
Published: (2020-03-01)

1: Iqgap1 Signaling Promotes Foreign Body Response To Biomedical Implants
by: Dharshan Sivaraj, BS, et al.
Published: (2021-07-01)

IQGAP1 Is a Phosphotyrosine-Regulated Scaffold for SH2-Containing Proteins
by: Louise Thines, et al.
Published: (2023-02-01)

IQGAP1 functions as a modulator of dishevelled nuclear localization in Wnt signaling.
by: Toshiyasu Goto, et al.
Published: (2013-01-01)

IQGAP1 is involved in post-ischemic neovascularization by regulating angiogenesis and macrophage infiltration.
by: Norifumi Urao, et al.
Published: (2010-10-01)

Role of e-cadherin in tumor metastasis and discovery of compounds targeting metastasis cancer cells
by: Onder, Tamer T
Published: (2008)

Enhancement of Migration and Invasion of Gastric Cancer Cells by IQGAP3
by: Natini Jinawath, et al.
Published: (2020-08-01)

Effective Prediction of Prostate Cancer Recurrence through the <i>IQGAP1</i> Network
by: Yan Gu, et al.
Published: (2021-01-01)

RhoC regulates the proliferation of gastric cancer cells through interaction with IQGAP1.
by: Yan Wu, et al.
Published: (2012-01-01)

Investigation of the role of chromosome missegregation in embryo development and in tumorigenesis
by: Burds, Aurora A. (Aurora Ann), 1973-
Published: (2005)

Identification of a novel metastasis enhancer, CDCP1, and analysis of its functions during melanoma metastasis
by: Liu, Hui
Published: (2009)

IQGAP scaffold proteins are the multifunctional regulators of cellular signaling and malignant transformation
by: P. A. Skovorodnikova, et al.
Published: (2017-07-01)

Glia Promote Synaptogenesis through an IQGAP PES-7 in C. elegans
by: Xiaohua Dong, et al.
Published: (2020-02-01)

The Dominant Negative IQGAP1(IR-WW) Domain as a Potential Therapy in Brain Cancer
by: Mahasin Osman
Published: (2023-05-01)

Correction: RhoC Regulates the Proliferation of Gastric Cancer Cells through Interaction with IQGAP1
Published: (2013-01-01)

The Overexpression of IQGAP1 and β-Catenin Is Associated with Tumor Progression in Hepatocellular Carcinoma In Vitro and In Vivo.
by: Xuewen Jin, et al.
Published: (2015-01-01)

Identification of IQGAP1 as a SLC26A4 (Pendrin)-Binding Protein in the Kidney
by: Jie Xu, et al.
Published: (2022-05-01)

Correction: RhoC Regulates the Proliferation of Gastric Cancer Cells through Interaction with IQGAP1.
by: Yan Wu, et al.
Published: (2013-01-01)

Targeted knockdown of IQGAP1 inhibits the progression of esophageal squamous cell carcinoma in vitro and in vivo.
by: Xiao-Xia Wang, et al.
Published: (2014-01-01)