Improved seed-based MR and CT image registration for prostate brachytherapy
Thesis (M. Eng.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2004.
| Main Author: | |
|---|---|
| Other Authors: | |
| Format: | Thesis |
| Language: | en_US |
| Published: |
Massachusetts Institute of Technology
2005
|
| Subjects: | |
| Online Access: | http://hdl.handle.net/1721.1/28690 |
| _version_ | 1826204345372246016 |
|---|---|
| author | Kim, Elizabeth S. (Elizabeth Seon-wha), 1979- |
| author2 | William M. Wells, III. |
| author_facet | William M. Wells, III. Kim, Elizabeth S. (Elizabeth Seon-wha), 1979- |
| author_sort | Kim, Elizabeth S. (Elizabeth Seon-wha), 1979- |
| collection | MIT |
| description | Thesis (M. Eng.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2004. |
| first_indexed | 2024-09-23T12:53:10Z |
| format | Thesis |
| id | mit-1721.1/28690 |
| institution | Massachusetts Institute of Technology |
| language | en_US |
| last_indexed | 2024-09-23T12:53:10Z |
| publishDate | 2005 |
| publisher | Massachusetts Institute of Technology |
| record_format | dspace |
| spelling | mit-1721.1/286902019-04-11T06:37:50Z Improved seed-based MR and CT image registration for prostate brachytherapy Improved seed-based magnetic resonance and computer tomography image registration for prostate brachytherapy Kim, Elizabeth S. (Elizabeth Seon-wha), 1979- William M. Wells, III. Massachusetts Institute of Technology. Dept. of Electrical Engineering and Computer Science. Massachusetts Institute of Technology. Dept. of Electrical Engineering and Computer Science. Electrical Engineering and Computer Science. Thesis (M. Eng.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2004. Includes bibliographical references (p. 73-76). Prostate cancer's high incidence and high survivability motivate its treatment using tightly focused radiation therapy. Brachytherapy treatment, the implantation of radioactive seeds into the prostate, is increasing in popularity, spurred by advances in medical imaging techniques for prostate visualization. Successful brachytherapy requires precise positioning of implant seeds within the pelvic anatomy. Following implantation, precise localization of individual seeds is required to evaluate treatment, but this remains an open challenge. This thesis addresses the seed localization problem with contributions for improving seed-based registration of MR and CT post-implant images. A model for non-rigid, affine prostate motion is presented and demonstrated to improve on current techniques of rigid registration. Also, an evaluation of the benefit of using multiple, rather than a few, seeds is presented, along with a scheme for validating registrations using manually detected seeds in MR and CT volumes. Finally, a scheme for automatic seed-based MR and CT registration by aligning all seeds is suggested, with supporting algorithms for CT seed-finding and unmatched feature registration. A call for an MR seed-finder is issued, for this is the final component needed to achieve automatic and complete seed-based MR and CT registration. by Elizabeth S. Kim. M.Eng. 2005-09-27T17:47:22Z 2005-09-27T17:47:22Z 2004 2004 Thesis http://hdl.handle.net/1721.1/28690 59007682 en_US M.I.T. theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. See provided URL for inquiries about permission. http://dspace.mit.edu/handle/1721.1/7582 76 p. 4267003 bytes 4274963 bytes application/pdf application/pdf application/pdf Massachusetts Institute of Technology |
| spellingShingle | Electrical Engineering and Computer Science. Kim, Elizabeth S. (Elizabeth Seon-wha), 1979- Improved seed-based MR and CT image registration for prostate brachytherapy |
| title | Improved seed-based MR and CT image registration for prostate brachytherapy |
| title_full | Improved seed-based MR and CT image registration for prostate brachytherapy |
| title_fullStr | Improved seed-based MR and CT image registration for prostate brachytherapy |
| title_full_unstemmed | Improved seed-based MR and CT image registration for prostate brachytherapy |
| title_short | Improved seed-based MR and CT image registration for prostate brachytherapy |
| title_sort | improved seed based mr and ct image registration for prostate brachytherapy |
| topic | Electrical Engineering and Computer Science. |
| url | http://hdl.handle.net/1721.1/28690 |
| work_keys_str_mv | AT kimelizabethselizabethseonwha1979 improvedseedbasedmrandctimageregistrationforprostatebrachytherapy AT kimelizabethselizabethseonwha1979 improvedseedbasedmagneticresonanceandcomputertomographyimageregistrationforprostatebrachytherapy |