Controllable vapor microbubbles for use in bioparticle actuation
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2003.
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| Format: | Thesis |
| Language: | eng |
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Massachusetts Institute of Technology
2006
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| Online Access: | http://hdl.handle.net/1721.1/29632 |
| _version_ | 1826203661019119616 |
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| author | Maxwell, Rebecca Braff, 1974- |
| author2 | Martin A. Schmidt, Mehmet Toner and Martha Gray. |
| author_facet | Martin A. Schmidt, Mehmet Toner and Martha Gray. Maxwell, Rebecca Braff, 1974- |
| author_sort | Maxwell, Rebecca Braff, 1974- |
| collection | MIT |
| description | Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2003. |
| first_indexed | 2024-09-23T12:41:05Z |
| format | Thesis |
| id | mit-1721.1/29632 |
| institution | Massachusetts Institute of Technology |
| language | eng |
| last_indexed | 2024-09-23T12:41:05Z |
| publishDate | 2006 |
| publisher | Massachusetts Institute of Technology |
| record_format | dspace |
| spelling | mit-1721.1/296322019-04-12T11:54:28Z Controllable vapor microbubbles for use in bioparticle actuation Maxwell, Rebecca Braff, 1974- Martin A. Schmidt, Mehmet Toner and Martha Gray. Massachusetts Institute of Technology. Dept. of Mechanical Engineering. Massachusetts Institute of Technology. Dept. of Mechanical Engineering. Mechanical Engineering. Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2003. Includes bibliographical references (p. 129-132). In this thesis, we present guidelines for using thermally formed microbubbles as a means of fluidic actuation. The use of microbubbles is attractive due to the simple fabrication and operation of such devices, however, prior work in this area was hindered by several issues inherent to vapor bubble formation that severely limited the reliability of bubble-based devices. It has been shown in this thesis that it is possible to control the location at which bubbles form and the size of the bubbles, as well as to achieve repeatable and reduced bubble formation temperature, and to create bubbles that collapse completely in less than 10 seconds. The achievement of controllable microbubbles makes possible many microfluidic applications, one of which we will demonstrate in this work. We have built a device that is capable of capturing, holding, and selectively releasing single bioparticles using microbubble actuation. This bioparticle actuator could be scaled into an array for the analysis of a large population of individual cells. by Rebecca Braff Maxwell. Ph.D. 2006-03-24T16:09:47Z 2006-03-24T16:09:47Z 2003 2003 Thesis http://hdl.handle.net/1721.1/29632 53371738 eng M.I.T. theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. See provided URL for inquiries about permission. http://dspace.mit.edu/handle/1721.1/7582 132 p. 6607954 bytes 6607763 bytes application/pdf application/pdf application/pdf Massachusetts Institute of Technology |
| spellingShingle | Mechanical Engineering. Maxwell, Rebecca Braff, 1974- Controllable vapor microbubbles for use in bioparticle actuation |
| title | Controllable vapor microbubbles for use in bioparticle actuation |
| title_full | Controllable vapor microbubbles for use in bioparticle actuation |
| title_fullStr | Controllable vapor microbubbles for use in bioparticle actuation |
| title_full_unstemmed | Controllable vapor microbubbles for use in bioparticle actuation |
| title_short | Controllable vapor microbubbles for use in bioparticle actuation |
| title_sort | controllable vapor microbubbles for use in bioparticle actuation |
| topic | Mechanical Engineering. |
| url | http://hdl.handle.net/1721.1/29632 |
| work_keys_str_mv | AT maxwellrebeccabraff1974 controllablevapormicrobubblesforuseinbioparticleactuation |