Cellular Gate Technology
We propose a biochemically plausible mechanism for constructing digital logic signals and gates of significant complexity within living cells. These mechanisms rely largely on co-opting existing biochemical machinery and binding proteins found naturally within the cell, replacing difficult protein e...
| Principais autores: | , |
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| Formato: | Artigo |
| Idioma: | en_US |
| Publicado em: |
First International Conference on UNCONVENTIONAL MODELS OF COMPUTATION, Auckland, New Zealand
2005
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| Acesso em linha: | http://hdl.handle.net/1721.1/29793 |
| _version_ | 1826206550846341120 |
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| author | Knight, Thomas F. Sussman, Gerald Jay |
| author2 | Massachusetts Institute of Technology. Department of Biological Engineering |
| author_facet | Massachusetts Institute of Technology. Department of Biological Engineering Knight, Thomas F. Sussman, Gerald Jay |
| author_sort | Knight, Thomas F. |
| collection | MIT |
| description | We propose a biochemically plausible mechanism for constructing digital logic signals and gates of significant complexity within living cells. These mechanisms rely largely on co-opting existing biochemical machinery and binding proteins found naturally within the cell, replacing difficult protein engineering problems with more straightforward engineering of novel combinations of gene control sequences and gene coding regions. The resulting logic technology, although slow, allows us to engineer the chemical behavior of cells for use as sensors and effectors. One promising use of such technology is the control of fabrication processes at the molecular scale. |
| first_indexed | 2024-09-23T13:34:42Z |
| format | Article |
| id | mit-1721.1/29793 |
| institution | Massachusetts Institute of Technology |
| language | en_US |
| last_indexed | 2025-03-10T11:31:23Z |
| publishDate | 2005 |
| publisher | First International Conference on UNCONVENTIONAL MODELS OF COMPUTATION, Auckland, New Zealand |
| record_format | dspace |
| spelling | mit-1721.1/297932025-02-27T21:05:22Z Cellular Gate Technology Knight, Thomas F. Sussman, Gerald Jay Massachusetts Institute of Technology. Department of Biological Engineering cellular gates molecular computing We propose a biochemically plausible mechanism for constructing digital logic signals and gates of significant complexity within living cells. These mechanisms rely largely on co-opting existing biochemical machinery and binding proteins found naturally within the cell, replacing difficult protein engineering problems with more straightforward engineering of novel combinations of gene control sequences and gene coding regions. The resulting logic technology, although slow, allows us to engineer the chemical behavior of cells for use as sensors and effectors. One promising use of such technology is the control of fabrication processes at the molecular scale. DARPA/ONR Ultrascale Computing Program under contract N00014-96-1-1228 and by the DARPA Embedded Computing Program under contract DABT63-95-C130. 2005-11-18T21:48:05Z 2005-11-18T21:48:05Z 1998-01-05 Article http://hdl.handle.net/1721.1/29793 en_US 1133836 bytes application/pdf application/pdf First International Conference on UNCONVENTIONAL MODELS OF COMPUTATION, Auckland, New Zealand |
| spellingShingle | cellular gates molecular computing Knight, Thomas F. Sussman, Gerald Jay Cellular Gate Technology |
| title | Cellular Gate Technology |
| title_full | Cellular Gate Technology |
| title_fullStr | Cellular Gate Technology |
| title_full_unstemmed | Cellular Gate Technology |
| title_short | Cellular Gate Technology |
| title_sort | cellular gate technology |
| topic | cellular gates molecular computing |
| url | http://hdl.handle.net/1721.1/29793 |
| work_keys_str_mv | AT knightthomasf cellulargatetechnology AT sussmangeraldjay cellulargatetechnology |