The engrailed homeodomain : determinants of DNA-binding affinity and specificity

The engrailed homeodomain : determinants of DNA-binding affinity and specificity

Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Biology, 1995.

Bibliographic Details
Main Author:	Ades, Sarah Ellen
Other Authors:	Robert T. Sauer.
Format:	Thesis
Language:	eng
Published:	Massachusetts Institute of Technology 2006
Subjects:	Biology
Online Access:	http://hdl.handle.net/1721.1/32174

Similar Items

DNA binding analysis of rare variants in homeodomains reveals homeodomain specificity-determining residues
by: Kian Hong Kock, et al.
Published: (2024-04-01)

Cognate DNA Recognition by Engrailed Homeodomain Involves a Conformational Change Controlled via an Electrostatic-Spring-Loaded Latch
by: Nicola D’Amelio, et al.
Published: (2022-02-01)

Side chain mobility and hydration in homeodomain-DNA recognition
by: Fraenkel, Ernest Samuel Benjamin, 1967-
Published: (2005)

Vsx2 controls eye organogenesis and retinal progenitor identity via homeodomain and non-homeodomain residues required for high affinity DNA binding.
by: Changjiang Zou, et al.
Published: (2012-09-01)

Functional specificity and design of transcription factor : the Oct-1 homeodomain
by: Pomerantz, Joel Leonard
Published: (2006)

Polycomb group proteins bind an engrailed PRE in both the "ON" and "OFF" transcriptional states of engrailed.
by: Kristofor K Langlais, et al.
Published: (2012-01-01)

A cationic motif upstream Engrailed2 homeodomain controls cell internalization through selective interaction with heparan sulfates
by: Sébastien Cardon, et al.
Published: (2023-04-01)

Binding polymorphism in the DNA bound state of the Pdx1 homeodomain.
by: Volodymyr Babin, et al.
Published: (2013-01-01)

Contribution of Distinct Homeodomain DNA Binding Specificities to Drosophila Embryonic Mesodermal Cell-Specific Gene Expression Programs
by: Busser, Brian W., et al.
Published: (2013)

Contribution of distinct homeodomain DNA binding specificities to Drosophila embryonic mesodermal cell-specific gene expression programs.
by: Brian W Busser, et al.
Published: (2013-01-01)

Affinity, Specificity, and Cooperativity of DNA Binding by Bacterial Gene Regulatory Proteins
by: Jannette Carey
Published: (2022-01-01)

Transcription Factor Binding Affinities and DNA Shape Readout
by: Max Schnepf, et al.
Published: (2020-11-01)

Intron insertion as a phylogenetic character: the engrailed homeobox of Strepsiptera does not indicate affinity with Diptera.
by: Rokas, A, et al.
Published: (1999)

Learned features of antibody-antigen binding affinity
by: Miller, Nathaniel L., et al.
Published: (2023)

Objective sequence-based subfamily classifications of mouse homeodomains reflect their in vitro DNA-binding preferences
by: Santos, Miguel A., et al.
Published: (2012)

Engrailed‐1 Promotes Pancreatic Cancer Metastasis
by: Jihao Xu, et al.
Published: (2024-02-01)

High-throughput sequencing SELEX for the determination of DNA-binding protein specificities in vitro
by: Raphaël Pantier, et al.
Published: (2022-09-01)

Inhibition of KDM4D and stabilisation of the PHF8 plant homeodomain’s transient structural states using antibodies
by: Wolfreys, F
Published: (2017)

Crystal Structure of the Double Homeodomain of DUX4 in Complex with DNA
by: John K. Lee, et al.
Published: (2018-12-01)

Binding affinity of a small molecule to an amorphous polymer in a solvent
by: Chunsrivirot, Surasak
Published: (2011)

Mammalian ETCHbox homeodomains
by: Lewin, T D, et al.
Published: (2021)

Genome-wide DNA binding pattern of the homeodomain transcription factor Sine oculis (So) in the developing eye of Drosophila melanogaster
by: Barbara Jusiak, et al.
Published: (2014-12-01)

DNA-binding specificity of the E2F gene family, and cloning and characterization of a novel family mamber
by: Fairchild, Brian A. (Brian Andrew), 1970-
Published: (2014)

Cyclization of a G4-specific peptide enhances its stability and G-quadruplex binding affinity
by: Ngo, Khac Huy, et al.
Published: (2022)

Differences in the binding affinities of ErbB family : heterogeneity in the prediction of resistance mutants
by: Verma, Chandra S., et al.
Published: (2014)

Physical organization of DNA by multiple non-specific DNA-binding modes of integration host factor (IHF)
by: Lin, Jie, et al.
Published: (2013)

Antagonism among DUX family members evolved from an ancestral toxic single homeodomain protein
by: Darko Bosnakovski, et al.
Published: (2023-10-01)

Investigating the ligandability of plant homeodomains
by: Bowkett, D
Published: (2015)

Specificity Residues Determine Binding Affinity for Two-Component Signal Transduction Systems
by: Jonathan W. Willett, et al.
Published: (2013-12-01)

The activity of engrailed imaginal disc enhancers is modulated epigenetically by chromatin and autoregulation.
by: Yuzhong Cheng, et al.
Published: (2023-11-01)

The Increased Expression of an Engrailed to Sustain Shell Formation in Response to Ocean Acidification
by: Yukun Zhang, et al.
Published: (2020-12-01)

Engrailed Homeoprotein Protects Mesencephalic Dopaminergic Neurons from Oxidative Stress
by: Hocine Rekaik, et al.
Published: (2015-10-01)

P22 arc--energetics and cooperativity of DNA binding
by: Brown, Bronwen Marylouise
Published: (2006)

Sequence-specific DNA binding by MYC/MAX to low-affinity non-E-box motifs.
by: Michael Allevato, et al.
Published: (2017-01-01)

Specificity of the Hox member Deformed is determined by transcription factor levels and binding site affinities
by: Pedro B. Pinto, et al.
Published: (2022-08-01)

A two-color bacterial two-hybrid system for selecting sequence-specific DNA-binding proteins via fluorescence activated cell sorting
by: Miller, Jeffrey Christopher, 1974-
Published: (2005)

Iron ions regulate antifungal HSAF biosynthesis in Lysobacter enzymogenes by manipulating the DNA-binding affinity of the ferric uptake regulator (Fur)
by: Bao Tang, et al.
Published: (2023-10-01)

On the prediction of protein-ligand structural complexes and binding affinities by hybrid statistical scoring function
by: Oon, Yu Yang
Published: (2023)

Engrailed 1 overexpression as a potential prognostic marker in Lower Grade Glioma
by: Jin Zhu, et al.
Published: (2019-09-01)

Auditory responses of engrailed and invected-expressing Johnston's Organ neurons in Drosophila melanogaster.
by: Adeline Pézier, et al.
Published: (2013-01-01)