The synthesis and applications of a biaryl-based asymmetric phosphine ligand
Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Chemistry, 2005.
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| Format: | Thesis |
| Language: | eng |
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Massachusetts Institute of Technology
2006
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| Online Access: | http://hdl.handle.net/1721.1/32490 |
| _version_ | 1811088239082078208 |
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| author | Hirai, Satoko |
| author2 | Stephen L. Buchwald. |
| author_facet | Stephen L. Buchwald. Hirai, Satoko |
| author_sort | Hirai, Satoko |
| collection | MIT |
| description | Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Chemistry, 2005. |
| first_indexed | 2024-09-23T13:58:54Z |
| format | Thesis |
| id | mit-1721.1/32490 |
| institution | Massachusetts Institute of Technology |
| language | eng |
| last_indexed | 2024-09-23T13:58:54Z |
| publishDate | 2006 |
| publisher | Massachusetts Institute of Technology |
| record_format | dspace |
| spelling | mit-1721.1/324902019-04-14T07:48:15Z The synthesis and applications of a biaryl-based asymmetric phosphine ligand Hirai, Satoko Stephen L. Buchwald. Massachusetts Institute of Technology. Dept. of Chemistry. Massachusetts Institute of Technology. Dept. of Chemistry. Chemistry. Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Chemistry, 2005. Includes bibliographical references. The asymmetric biaryl backbone of a dialkylbiphenyl phosphine ligand was developed, synthesized, and resolved. The application of the chiral phosphine ligand to the asymmetric Suzuki-Miyaura cross-coupling reaction was also investigated. This phosphine ligand has yielded promising results in the asymmetric Suzuki-coupling of hindered boronic acids with the electron-rich aryl bromide, 1-bromo-2- methoxynaphthalene, to synthesize biaryls in modest enantioselectivity. by Satoko Hirai. S.M. 2006-03-29T18:49:22Z 2006-03-29T18:49:22Z 2005 2005 Thesis http://hdl.handle.net/1721.1/32490 61858035 eng M.I.T. theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. See provided URL for inquiries about permission. http://dspace.mit.edu/handle/1721.1/7582 64 p. 2246142 bytes 2247943 bytes application/pdf application/pdf application/pdf Massachusetts Institute of Technology |
| spellingShingle | Chemistry. Hirai, Satoko The synthesis and applications of a biaryl-based asymmetric phosphine ligand |
| title | The synthesis and applications of a biaryl-based asymmetric phosphine ligand |
| title_full | The synthesis and applications of a biaryl-based asymmetric phosphine ligand |
| title_fullStr | The synthesis and applications of a biaryl-based asymmetric phosphine ligand |
| title_full_unstemmed | The synthesis and applications of a biaryl-based asymmetric phosphine ligand |
| title_short | The synthesis and applications of a biaryl-based asymmetric phosphine ligand |
| title_sort | synthesis and applications of a biaryl based asymmetric phosphine ligand |
| topic | Chemistry. |
| url | http://hdl.handle.net/1721.1/32490 |
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