Fabrication of a picoliter microreactor with multilayer elastomer values
Thesis (S.B.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2005.
Main Author: | |
---|---|
Other Authors: | |
Format: | Thesis |
Language: | eng |
Published: |
Massachusetts Institute of Technology
2006
|
Subjects: | |
Online Access: | http://hdl.handle.net/1721.1/32916 |
_version_ | 1811094494775345152 |
---|---|
author | Smith, Emily (Emily C.) |
author2 | Todd Thorsen. |
author_facet | Todd Thorsen. Smith, Emily (Emily C.) |
author_sort | Smith, Emily (Emily C.) |
collection | MIT |
description | Thesis (S.B.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2005. |
first_indexed | 2024-09-23T16:00:34Z |
format | Thesis |
id | mit-1721.1/32916 |
institution | Massachusetts Institute of Technology |
language | eng |
last_indexed | 2024-09-23T16:00:34Z |
publishDate | 2006 |
publisher | Massachusetts Institute of Technology |
record_format | dspace |
spelling | mit-1721.1/329162019-04-12T09:24:21Z Fabrication of a picoliter microreactor with multilayer elastomer values Smith, Emily (Emily C.) Todd Thorsen. Massachusetts Institute of Technology. Dept. of Mechanical Engineering. Massachusetts Institute of Technology. Dept. of Mechanical Engineering. Mechanical Engineering. Thesis (S.B.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2005. Includes bibliographical references (leaves 45-46). Microfluidics has the ability to greatly reduce the time needed to do many biological tests. The development of polymers has brought about substrates with elastomeric properties that can be used to the advantage of microfluidic device design. Elastomeric polymers can be used to create small scale passive valve systems. These valves can compartmentalize reactions in devices. Current microreactors only allow researchers to do one test at a time. Devices with the capability to compartmentalize reactions using valves could perform multiple reactions simultaneously. This thesis details the fabrication and design of a microreactor that can maintain cells in the device after a reaction. The fabrication of the device was done without a clean room and using no specialized equipment. Creation of the device and using it for testing requires little training and takes less time than performing the test using conventional methods. The device could readily be made and used by researchers using equipment already in their lab and is cheaper than current devices on the market. by Emily Smith. S.B. 2006-05-15T20:39:04Z 2006-05-15T20:39:04Z 2005 2005 Thesis http://hdl.handle.net/1721.1/32916 62763523 eng M.I.T. theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. See provided URL for inquiries about permission. http://dspace.mit.edu/handle/1721.1/7582 46 leaves 1937593 bytes 1937863 bytes application/pdf application/pdf application/pdf Massachusetts Institute of Technology |
spellingShingle | Mechanical Engineering. Smith, Emily (Emily C.) Fabrication of a picoliter microreactor with multilayer elastomer values |
title | Fabrication of a picoliter microreactor with multilayer elastomer values |
title_full | Fabrication of a picoliter microreactor with multilayer elastomer values |
title_fullStr | Fabrication of a picoliter microreactor with multilayer elastomer values |
title_full_unstemmed | Fabrication of a picoliter microreactor with multilayer elastomer values |
title_short | Fabrication of a picoliter microreactor with multilayer elastomer values |
title_sort | fabrication of a picoliter microreactor with multilayer elastomer values |
topic | Mechanical Engineering. |
url | http://hdl.handle.net/1721.1/32916 |
work_keys_str_mv | AT smithemilyemilyc fabricationofapicolitermicroreactorwithmultilayerelastomervalues |