Modeling and analysis of single-molecule experiments
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemistry, 2005.
| Main Author: | |
|---|---|
| Other Authors: | |
| Format: | Thesis |
| Language: | eng |
| Published: |
Massachusetts Institute of Technology
2007
|
| Subjects: | |
| Online Access: | http://dspace.mit.edu/handle/1721.1/33654 http://hdl.handle.net/1721.1/33654 |
| _version_ | 1826211222259761152 |
|---|---|
| author | Witkoskie, James B |
| author2 | Jianshu Cao. |
| author_facet | Jianshu Cao. Witkoskie, James B |
| author_sort | Witkoskie, James B |
| collection | MIT |
| description | Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemistry, 2005. |
| first_indexed | 2024-09-23T15:02:32Z |
| format | Thesis |
| id | mit-1721.1/33654 |
| institution | Massachusetts Institute of Technology |
| language | eng |
| last_indexed | 2024-09-23T15:02:32Z |
| publishDate | 2007 |
| publisher | Massachusetts Institute of Technology |
| record_format | dspace |
| spelling | mit-1721.1/336542019-04-10T12:12:30Z Modeling and analysis of single-molecule experiments Witkoskie, James B Jianshu Cao. Massachusetts Institute of Technology. Dept. of Chemistry. Massachusetts Institute of Technology. Dept. of Chemistry. Chemistry. Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemistry, 2005. Vita. Includes bibliographical references (p. 281-311). Single molecule experiments offer a unique window into the molecular world. This window allows us to distinguish the behaviors of individual molecules from the behavior of bulk by observing rare events and heterogeneity in the dynamics. This thesis discusses both models for single molecule experiments, including the stretching of DNA in hydrodynamic flows and the diffusion of tracer particles in heterogeneous environments, and methods to analyze single molecule data to allow determination of properties and models for single molecule experiments. These methods of analysis are based on combining information theory and Bayesian methods with physical insight and are applied to several experimental situations. by James B. Witkoskie. Ph.D. 2007-02-20T15:30:03Z 2007-02-20T15:30:03Z 2005 2005 Thesis http://dspace.mit.edu/handle/1721.1/33654 http://hdl.handle.net/1721.1/33654 64551507 eng M.I.T. theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. See provided URL for inquiries about permission. http://dspace.mit.edu/handle/1721.1/33654 http://dspace.mit.edu/handle/1721.1/7582 313, 3 p. application/pdf Massachusetts Institute of Technology |
| spellingShingle | Chemistry. Witkoskie, James B Modeling and analysis of single-molecule experiments |
| title | Modeling and analysis of single-molecule experiments |
| title_full | Modeling and analysis of single-molecule experiments |
| title_fullStr | Modeling and analysis of single-molecule experiments |
| title_full_unstemmed | Modeling and analysis of single-molecule experiments |
| title_short | Modeling and analysis of single-molecule experiments |
| title_sort | modeling and analysis of single molecule experiments |
| topic | Chemistry. |
| url | http://dspace.mit.edu/handle/1721.1/33654 http://hdl.handle.net/1721.1/33654 |
| work_keys_str_mv | AT witkoskiejamesb modelingandanalysisofsinglemoleculeexperiments |