Auditory-nerve fiber responses to amplitude modulated tones and multi-tonal stimuli
Thesis (S.M.)--Harvard-MIT Division of Health Sciences and Technology, 2005.
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| Format: | Thesis |
| Language: | eng |
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Massachusetts Institute of Technology
2006
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| Online Access: | http://hdl.handle.net/1721.1/33844 |
| _version_ | 1826207629770227712 |
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| author | Cheng, Holden |
| author2 | John J. Guinan, Jr. |
| author_facet | John J. Guinan, Jr. Cheng, Holden |
| author_sort | Cheng, Holden |
| collection | MIT |
| description | Thesis (S.M.)--Harvard-MIT Division of Health Sciences and Technology, 2005. |
| first_indexed | 2024-09-23T13:52:32Z |
| format | Thesis |
| id | mit-1721.1/33844 |
| institution | Massachusetts Institute of Technology |
| language | eng |
| last_indexed | 2024-09-23T13:52:32Z |
| publishDate | 2006 |
| publisher | Massachusetts Institute of Technology |
| record_format | dspace |
| spelling | mit-1721.1/338442019-04-10T18:16:52Z Auditory-nerve fiber responses to amplitude modulated tones and multi-tonal stimuli ANF responses to AM tones and multi-tonal stimuli Cheng, Holden John J. Guinan, Jr. Harvard University--MIT Division of Health Sciences and Technology. Harvard University--MIT Division of Health Sciences and Technology. Harvard University--MIT Division of Health Sciences and Technology. Thesis (S.M.)--Harvard-MIT Division of Health Sciences and Technology, 2005. Includes bibliographical references (leaves 35-36). In normal-hearing ears, sound waves are amplified within the cochlea and a small fraction of the sound energy travels backward out into the ear canal, producing sounds known as "otoacoustic emissions" (OAE) that can be measured with a sensitive microphone. One class of OAE, called "stimulus-frequency-otoacoustic-emissions" (SFOAEs), has been hypothesized to be produced by a process known as "coherent reflection filtering" (CRF). The CRF theory provides a prediction between the SFOAE group delay and the group delays of tone responses on the basilar membrane within the cochlea. Using single and multiple-tone stimuli, we collected data from the firing patterns of single auditory-nerve-fibers (ANFs) from which basilar-membrane tone-response group delays can be calculated for both high and low best-frequency (BF) positions along the basilar membrane. These calculated basilar-membrane group delays were compared to published SFOAE group delays. Our results suggest that group delays calculated from the tip, the lower-frequency tail, or the above-BF region of ANF tuning curves do not match the CRF theory prediction. In obtaining the data to the test the CRF theory, we used two methods for obtaining ANF group delays at frequencies above BF: a previously published method and a simpler new method based on the same principle. (cont.) Surprisingly, the two methods produced different results. Control measurements suggest that the previously published method does not do what it was expected to do. by Holden Cheng. S.M. 2006-08-25T18:50:25Z 2006-08-25T18:50:25Z 2005 2005 Thesis http://hdl.handle.net/1721.1/33844 65466288 eng M.I.T. theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. See provided URL for inquiries about permission. http://dspace.mit.edu/handle/1721.1/7582 36 leaves 1605595 bytes 1606988 bytes application/pdf application/pdf application/pdf Massachusetts Institute of Technology |
| spellingShingle | Harvard University--MIT Division of Health Sciences and Technology. Cheng, Holden Auditory-nerve fiber responses to amplitude modulated tones and multi-tonal stimuli |
| title | Auditory-nerve fiber responses to amplitude modulated tones and multi-tonal stimuli |
| title_full | Auditory-nerve fiber responses to amplitude modulated tones and multi-tonal stimuli |
| title_fullStr | Auditory-nerve fiber responses to amplitude modulated tones and multi-tonal stimuli |
| title_full_unstemmed | Auditory-nerve fiber responses to amplitude modulated tones and multi-tonal stimuli |
| title_short | Auditory-nerve fiber responses to amplitude modulated tones and multi-tonal stimuli |
| title_sort | auditory nerve fiber responses to amplitude modulated tones and multi tonal stimuli |
| topic | Harvard University--MIT Division of Health Sciences and Technology. |
| url | http://hdl.handle.net/1721.1/33844 |
| work_keys_str_mv | AT chengholden auditorynervefiberresponsestoamplitudemodulatedtonesandmultitonalstimuli AT chengholden anfresponsestoamtonesandmultitonalstimuli |