Estimation of nonlinear mechanical properties of atherosclerotic plaques
Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2005.
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| Format: | Thesis |
| Language: | eng |
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Massachusetts Institute of Technology
2006
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| Online Access: | http://hdl.handle.net/1721.1/33907 |
| _version_ | 1826216783818784768 |
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| author | Zhu, Ting F. (Ting Fredrick) |
| author2 | Roger D. Kamm and Mohammad R. Kaazempur Mofrad. |
| author_facet | Roger D. Kamm and Mohammad R. Kaazempur Mofrad. Zhu, Ting F. (Ting Fredrick) |
| author_sort | Zhu, Ting F. (Ting Fredrick) |
| collection | MIT |
| description | Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2005. |
| first_indexed | 2024-09-23T16:53:22Z |
| format | Thesis |
| id | mit-1721.1/33907 |
| institution | Massachusetts Institute of Technology |
| language | eng |
| last_indexed | 2024-09-23T16:53:22Z |
| publishDate | 2006 |
| publisher | Massachusetts Institute of Technology |
| record_format | dspace |
| spelling | mit-1721.1/339072019-04-12T09:46:28Z Estimation of nonlinear mechanical properties of atherosclerotic plaques Zhu, Ting F. (Ting Fredrick) Roger D. Kamm and Mohammad R. Kaazempur Mofrad. Massachusetts Institute of Technology. Dept. of Mechanical Engineering. Massachusetts Institute of Technology. Dept. of Mechanical Engineering. Mechanical Engineering. Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2005. Includes bibliographical references (leaves 57-59). A numerical method has been developed to estimate the mechanical properties of atherosclerotic plaques by combining genetic algorithm with finite element methods. Plaque images derived from optical coherence tomography were employed to construct finite element models which were subsequently used in conjunction with a genetic algorithm to determine the parameters in a nonlinear constitutive model. A new multi-frame scheme is introduced to better perform the estimation on a nonlinear mechanical model and reduce the effects of noise. Results show while it is feasible to estimate the nonlinear mechanical properties of plaque, the accuracy can depend on various factors, especially the noise. KEY woRDS: FEM, atherosclerotic plaques, parameter estimation, Mooney-Rivlin model, optical coherence tomography, image noise. by Ting F. Zhu. S.M. 2006-08-25T18:55:43Z 2006-08-25T18:55:43Z 2005 2005 Thesis http://hdl.handle.net/1721.1/33907 66910312 eng M.I.T. theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. See provided URL for inquiries about permission. http://dspace.mit.edu/handle/1721.1/7582 91 leaves 3195834 bytes 3199589 bytes application/pdf application/pdf application/pdf Massachusetts Institute of Technology |
| spellingShingle | Mechanical Engineering. Zhu, Ting F. (Ting Fredrick) Estimation of nonlinear mechanical properties of atherosclerotic plaques |
| title | Estimation of nonlinear mechanical properties of atherosclerotic plaques |
| title_full | Estimation of nonlinear mechanical properties of atherosclerotic plaques |
| title_fullStr | Estimation of nonlinear mechanical properties of atherosclerotic plaques |
| title_full_unstemmed | Estimation of nonlinear mechanical properties of atherosclerotic plaques |
| title_short | Estimation of nonlinear mechanical properties of atherosclerotic plaques |
| title_sort | estimation of nonlinear mechanical properties of atherosclerotic plaques |
| topic | Mechanical Engineering. |
| url | http://hdl.handle.net/1721.1/33907 |
| work_keys_str_mv | AT zhutingftingfredrick estimationofnonlinearmechanicalpropertiesofatheroscleroticplaques |