Fabrication and control of microfluidic devices for on-chip synthesis
Includes bibliographical references (p. 19).
| Main Author: | |
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| Other Authors: | |
| Format: | Thesis |
| Language: | eng |
| Published: |
Massachusetts Institute of Technology
2006
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| Subjects: | |
| Online Access: | http://hdl.handle.net/1721.1/35066 |
| _version_ | 1811086128043786240 |
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| author | Hsu, Byron B. |
| author2 | Joseph M. Jacobson. |
| author_facet | Joseph M. Jacobson. Hsu, Byron B. |
| author_sort | Hsu, Byron B. |
| collection | MIT |
| description | Includes bibliographical references (p. 19). |
| first_indexed | 2024-09-23T13:21:17Z |
| format | Thesis |
| id | mit-1721.1/35066 |
| institution | Massachusetts Institute of Technology |
| language | eng |
| last_indexed | 2024-09-23T13:21:17Z |
| publishDate | 2006 |
| publisher | Massachusetts Institute of Technology |
| record_format | dspace |
| spelling | mit-1721.1/350662019-04-12T15:42:56Z Fabrication and control of microfluidic devices for on-chip synthesis Hsu, Byron B. Joseph M. Jacobson. Massachusetts Institute of Technology. Dept. of Materials Science and Engineering. Massachusetts Institute of Technology. Dept. of Materials Science and Engineering. Materials Science and Engineering. Includes bibliographical references (p. 19). Thesis (S.B.)--Massachusetts Institute of Technology, Dept. of Materials Science and Engineering, 2006. Introduction: In biological research today, there is great demand for synthesized biological compounds. The sequencing of the Human Genome has been completed, as well as that of many other organisms. Current work is now shifting towards the production of biological macromolecules. More specifically, this includes gene and genome synthesis from user-defined sequences. A series of A, T, G, and C nucleotides are specified in advance, and then constructed. Because of the error rates in perfectly synthesizing these specific DNA chains, it is more efficient to synthesize smaller oligonudeotide chains (oligos) and then allow them to self-assemble them into a larger oligos. These assembled chains are then brought together to form even longer chains, in a repeating process known as hierarchical assembly. by Byron Hsu. S.B. 2006-12-18T20:01:36Z 2006-12-18T20:01:36Z 2006 2006 Thesis http://hdl.handle.net/1721.1/35066 71229963 eng M.I.T. theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. See provided URL for inquiries about permission. http://dspace.mit.edu/handle/1721.1/7582 19 p. 850255 bytes 848034 bytes application/pdf application/pdf application/pdf Massachusetts Institute of Technology |
| spellingShingle | Materials Science and Engineering. Hsu, Byron B. Fabrication and control of microfluidic devices for on-chip synthesis |
| title | Fabrication and control of microfluidic devices for on-chip synthesis |
| title_full | Fabrication and control of microfluidic devices for on-chip synthesis |
| title_fullStr | Fabrication and control of microfluidic devices for on-chip synthesis |
| title_full_unstemmed | Fabrication and control of microfluidic devices for on-chip synthesis |
| title_short | Fabrication and control of microfluidic devices for on-chip synthesis |
| title_sort | fabrication and control of microfluidic devices for on chip synthesis |
| topic | Materials Science and Engineering. |
| url | http://hdl.handle.net/1721.1/35066 |
| work_keys_str_mv | AT hsubyronb fabricationandcontrolofmicrofluidicdevicesforonchipsynthesis |