Synthesis and Complexation Behavior of Pluronic-b-Poly(acrylic Acid) Copolymer with Doxorubicin
Poly(acrylic acid) (PAA) was attached on both termini of Pluronic P85 copolymer (EO27PO39EO27)) via atom transfer radical polymerization (ATRP) to produce a novel block copolymer, PAA-b-P85-b-PAA (P85PAA). The P85PAA-DOX complex formation and drug loading were strongly dependent on the PAA segment a...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
2007
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| Subjects: | |
| Online Access: | http://hdl.handle.net/1721.1/35873 |