Synthesis and Complexation Behavior of Pluronic-b-Poly(acrylic Acid) Copolymer with Doxorubicin

Synthesis and Complexation Behavior of Pluronic-b-Poly(acrylic Acid) Copolymer with Doxorubicin

Poly(acrylic acid) (PAA) was attached on both termini of Pluronic P85 copolymer (EO27PO39EO27)) via atom transfer radical polymerization (ATRP) to produce a novel block copolymer, PAA-b-P85-b-PAA (P85PAA). The P85PAA-DOX complex formation and drug loading were strongly dependent on the PAA segment a...

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Bibliographic Details
Main Authors:	Tian, Y., Tam, Michael K. C., Hatton, T. Alan, Bromberg, Lev
Format:	Article
Language:	English
Published:	2007
Subjects:	Doxorubicin Atom Transfer Radical Polymerization Pluronic P85
Online Access:	http://hdl.handle.net/1721.1/35873

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