Exploration of large scale manufacturing of polydimethylsiloxane (PDMS) microfluidic devices
Thesis (S.B.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2006.
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| Format: | Thesis |
| Language: | eng |
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Massachusetts Institute of Technology
2007
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| Online Access: | http://hdl.handle.net/1721.1/36748 |
| _version_ | 1811068844235554816 |
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| author | Hum, Philip W. (Philip Wing-Jung) |
| author2 | David E. Hardt. |
| author_facet | David E. Hardt. Hum, Philip W. (Philip Wing-Jung) |
| author_sort | Hum, Philip W. (Philip Wing-Jung) |
| collection | MIT |
| description | Thesis (S.B.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2006. |
| first_indexed | 2024-09-23T08:01:55Z |
| format | Thesis |
| id | mit-1721.1/36748 |
| institution | Massachusetts Institute of Technology |
| language | eng |
| last_indexed | 2024-09-23T08:01:55Z |
| publishDate | 2007 |
| publisher | Massachusetts Institute of Technology |
| record_format | dspace |
| spelling | mit-1721.1/367482022-01-13T07:54:36Z Exploration of large scale manufacturing of polydimethylsiloxane (PDMS) microfluidic devices Hum, Philip W. (Philip Wing-Jung) David E. Hardt. Massachusetts Institute of Technology. Dept. of Mechanical Engineering. Massachusetts Institute of Technology. Department of Mechanical Engineering Mechanical Engineering. Thesis (S.B.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2006. Includes bibliographical references (leaves 54-56). Discussion of the current manufacturing process of polydimethylsiloxane (PDMS) parts and the emergence of PDMS use in biomedical microfluidic devices addresses the need to develop large scale manufacturing processes for the fabrication of said devices. Casting PDMS parts is found to be the best mass production process after evaluating several different production methods. Automation of the manufacturing process is introduced as a solution to the need for mass production. Changing variables within the production process and its effects are also discussed with the recommendation being made for using low viscosity pre-cured PDMS, high temperature curing and high vacuum degassing techniques to produce high quality parts at high production rates. The further development of producing two-sided PDMS parts is recommended by investigating the usage of a non-closed aspect limited casting process. by Philip W. Hum. S.B. 2007-03-12T17:50:07Z 2007-03-12T17:50:07Z 2006 2006 Thesis http://hdl.handle.net/1721.1/36748 78263832 eng M.I.T. theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. See provided URL for inquiries about permission. http://dspace.mit.edu/handle/1721.1/7582 56 leaves application/pdf Massachusetts Institute of Technology |
| spellingShingle | Mechanical Engineering. Hum, Philip W. (Philip Wing-Jung) Exploration of large scale manufacturing of polydimethylsiloxane (PDMS) microfluidic devices |
| title | Exploration of large scale manufacturing of polydimethylsiloxane (PDMS) microfluidic devices |
| title_full | Exploration of large scale manufacturing of polydimethylsiloxane (PDMS) microfluidic devices |
| title_fullStr | Exploration of large scale manufacturing of polydimethylsiloxane (PDMS) microfluidic devices |
| title_full_unstemmed | Exploration of large scale manufacturing of polydimethylsiloxane (PDMS) microfluidic devices |
| title_short | Exploration of large scale manufacturing of polydimethylsiloxane (PDMS) microfluidic devices |
| title_sort | exploration of large scale manufacturing of polydimethylsiloxane pdms microfluidic devices |
| topic | Mechanical Engineering. |
| url | http://hdl.handle.net/1721.1/36748 |
| work_keys_str_mv | AT humphilipwphilipwingjung explorationoflargescalemanufacturingofpolydimethylsiloxanepdmsmicrofluidicdevices |