Assisted auscultation : creation and visualization of high dimensional feature spaces for the detection of mitral regurgitation

Thesis (M. Eng.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, June 2006.

Bibliographic Details
Main Author: Leeds, Daniel Demeny
Other Authors: John V. Guttag.
Format: Thesis
Language:eng
Published: Massachusetts Institute of Technology 2007
Subjects:
Online Access:http://hdl.handle.net/1721.1/36806
_version_ 1826193865578643456
author Leeds, Daniel Demeny
author2 John V. Guttag.
author_facet John V. Guttag.
Leeds, Daniel Demeny
author_sort Leeds, Daniel Demeny
collection MIT
description Thesis (M. Eng.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, June 2006.
first_indexed 2024-09-23T09:46:32Z
format Thesis
id mit-1721.1/36806
institution Massachusetts Institute of Technology
language eng
last_indexed 2024-09-23T09:46:32Z
publishDate 2007
publisher Massachusetts Institute of Technology
record_format dspace
spelling mit-1721.1/368062019-04-10T09:05:28Z Assisted auscultation : creation and visualization of high dimensional feature spaces for the detection of mitral regurgitation Leeds, Daniel Demeny John V. Guttag. Massachusetts Institute of Technology. Dept. of Electrical Engineering and Computer Science. Massachusetts Institute of Technology. Dept. of Electrical Engineering and Computer Science. Electrical Engineering and Computer Science. Thesis (M. Eng.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, June 2006. "May 2006." Includes bibliographical references (p. 83-84). Cardiac auscultation, listening to the heart using a stethoscope, often constitutes the first step in detection of common heart problems. Unfortunately, primary care physicians, who perform this initial screening, often lack the experience to correctly evaluate what they hear. False referrals are frequent, costing hundreds of dollars and hours of time for many patients. We report on a system we have built to aid medical practitioners in diagnosing Mitral Regurgitation (MR) based on heart sounds. Our work builds on the "prototypical beat" introduced by Syed in [17] to extract two different feature sets characterizing systolic acoustic activity. One feature set is derived from current medical knowledge. The other is based on unsupervised learning of systolic shapes, using component Analysis. Our system employs self-organizing maps (SOMs) to depict the distribution of patients in each feature space as labels within a two-dimensional colored grid. A user screens new patients by viewing their projections onto the SOM, and determining whether they are closer in space, and thus more similar, to patients with or without MR. We evaluated our system on 46 patients. Using a combination of the two feature sets, SOM-based diagnosis classified patients with accuracy similar to that of a cardiologist. by Daniel Demeny Leeds. M.Eng. 2007-03-12T17:55:29Z 2007-03-12T17:55:29Z 2006 Thesis http://hdl.handle.net/1721.1/36806 80768708 eng M.I.T. theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. See provided URL for inquiries about permission. http://dspace.mit.edu/handle/1721.1/7582 83 p. application/pdf Massachusetts Institute of Technology
spellingShingle Electrical Engineering and Computer Science.
Leeds, Daniel Demeny
Assisted auscultation : creation and visualization of high dimensional feature spaces for the detection of mitral regurgitation
title Assisted auscultation : creation and visualization of high dimensional feature spaces for the detection of mitral regurgitation
title_full Assisted auscultation : creation and visualization of high dimensional feature spaces for the detection of mitral regurgitation
title_fullStr Assisted auscultation : creation and visualization of high dimensional feature spaces for the detection of mitral regurgitation
title_full_unstemmed Assisted auscultation : creation and visualization of high dimensional feature spaces for the detection of mitral regurgitation
title_short Assisted auscultation : creation and visualization of high dimensional feature spaces for the detection of mitral regurgitation
title_sort assisted auscultation creation and visualization of high dimensional feature spaces for the detection of mitral regurgitation
topic Electrical Engineering and Computer Science.
url http://hdl.handle.net/1721.1/36806
work_keys_str_mv AT leedsdanieldemeny assistedauscultationcreationandvisualizationofhighdimensionalfeaturespacesforthedetectionofmitralregurgitation