Molecular Computations for the Stabilization of Therapeutic Proteins
Molecular computations based on quantum mechanics and statistical mechanics have been applied to the understanding and quantification of processes leading to the degradation of therapeutic proteins. In particular, we focus on oxidation and aggregation. Specifically, two reactions, hydrogen transfer...
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Format: | Article |
Language: | en_US |
Published: |
2003
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Online Access: | http://hdl.handle.net/1721.1/3932 |