Synthetic Viral Genomics: Risks and Benefits for Science and Society

Technical Report in support of Sloan Foundation sponsored study on DNA synthesis governance options

Bibliographic Details
Main Author: Baric, Ralph
Format: Technical Report
Language:en_US
Published: 2007
Subjects:
Online Access:http://hdl.handle.net/1721.1/39652
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author Baric, Ralph
author_facet Baric, Ralph
author_sort Baric, Ralph
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description Technical Report in support of Sloan Foundation sponsored study on DNA synthesis governance options
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spelling mit-1721.1/396522019-04-12T09:30:43Z Synthetic Viral Genomics: Risks and Benefits for Science and Society Baric, Ralph synthetic biology Technical Report in support of Sloan Foundation sponsored study on DNA synthesis governance options Viral disease outbreaks have long inspired fear in human populations. Highly pathogenic infectious disease has shaped world history, primarily by impacting the outcome of wars and other global conflicts and precipitating human movement. Historic accounts have documented the catastrophic consequences and human suffering associated with widespread viral outbreaks like smallpox virus, yellow fever virus, measles virus, human immunodeficiency virus (HIV), the severe acute respiratory syndrome coronavirus (SARS-CoV), the 1918 influenza virus and others (51). News accounts and film have reinforced the serious threat posed by the emergence of new viral diseases as well as the catastrophic consequences of intentional release of highly pathogenic viruses in human populations. As illustrated by the SARS epidemic and the continuing evolution of the H5N1 avian influenza, global and national infectious disease outbreaks can overwhelm disaster medical response networks and medical facilities, disrupt global economies, and paralyze health and medical services by targeting health care workers and medical staff (21). This review focuses on viruses of humans, animals and plants that are viewed as potential weapons of mass disruption to human populations, critical plant and animal food sources, and national economies; and will consider whether and how the availability of synthetic genomics technologies will change this landscape. 2007-12-04T17:28:00Z 2007-12-04T17:28:00Z 2007-12-04T17:28:00Z Technical Report http://hdl.handle.net/1721.1/39652 en_US application/pdf
spellingShingle synthetic biology
Baric, Ralph
Synthetic Viral Genomics: Risks and Benefits for Science and Society
title Synthetic Viral Genomics: Risks and Benefits for Science and Society
title_full Synthetic Viral Genomics: Risks and Benefits for Science and Society
title_fullStr Synthetic Viral Genomics: Risks and Benefits for Science and Society
title_full_unstemmed Synthetic Viral Genomics: Risks and Benefits for Science and Society
title_short Synthetic Viral Genomics: Risks and Benefits for Science and Society
title_sort synthetic viral genomics risks and benefits for science and society
topic synthetic biology
url http://hdl.handle.net/1721.1/39652
work_keys_str_mv AT baricralph syntheticviralgenomicsrisksandbenefitsforscienceandsociety