A wearable blood pressure sensor using oscillometric photoplethysmography and micro accelerometers
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2007.
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| Format: | Thesis |
| Language: | eng |
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Massachusetts Institute of Technology
2008
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| Online Access: | http://hdl.handle.net/1721.1/40363 |
| _version_ | 1826196561489559552 |
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| author | Shaltis, Phillip Andrew |
| author2 | H. Harry Asada. |
| author_facet | H. Harry Asada. Shaltis, Phillip Andrew |
| author_sort | Shaltis, Phillip Andrew |
| collection | MIT |
| description | Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2007. |
| first_indexed | 2024-09-23T10:29:30Z |
| format | Thesis |
| id | mit-1721.1/40363 |
| institution | Massachusetts Institute of Technology |
| language | eng |
| last_indexed | 2024-09-23T10:29:30Z |
| publishDate | 2008 |
| publisher | Massachusetts Institute of Technology |
| record_format | dspace |
| spelling | mit-1721.1/403632022-01-13T07:54:36Z A wearable blood pressure sensor using oscillometric photoplethysmography and micro accelerometers Shaltis, Phillip Andrew H. Harry Asada. Massachusetts Institute of Technology. Dept. of Mechanical Engineering. Massachusetts Institute of Technology. Department of Mechanical Engineering Mechanical Engineering. Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2007. Includes bibliographical references (leaves 119-124). Monitoring arterial blood pressure (ABP) with a sensor virtually imperceptible to the wearer, for continuous periods of weeks, months, or years, could prove revolutionary in the diagnosis and treatment of chronic hypertension and heart failure, as well as a monitoring tool for convalescing individuals, and individuals in hazardous duty (such as firefighters or soldiers). To this end, a miniaturizable, non-invasive blood pressure sensor is designed and validated. A solid, coin-sized cuff-less photoplethysmography (PPG) sensor worn over a palpable artery is utilized to measure arterial blood pressure. Measurements are obtained through a modified oscillometric technique which eliminates the need for a high pressure cuff and instead, takes advantage of natural hydrostatic pressure changes caused by raising and lowering the subject's arm. In this work, the principle of hydrostatic oscillometry is first detailed. To better understand the internal mechanisms of pressure propagation within the tissue, a comprehensive non-linear finite element model of the finger base is constructed and validated using a combination of magnetic resonance imaging and experimental tissue stiffness measurements. (cont.) A prototype finger blood pressure monitor is designed and constructed in combination with a novel accelerometer-based height sensor. The 95% confidence interval for a Bland-Altman comparison between the proposed sensor's mean arterial pressure (MAP) measurements and the simultaneous Finapres MAP measurements is [+919, -283] Pa ([+6.91, -9.04] mmHg). The percent difference between the two methods is shown to be 3.0%. A method for continuous MAP measurements utilizing the sensor system is proposed and is shown to be capable of providing reliable measurements for several minutes. by Phillip Andrew Shaltis. Ph.D. 2008-02-27T22:13:59Z 2008-02-27T22:13:59Z 2007 2007 Thesis http://hdl.handle.net/1721.1/40363 188049322 eng M.I.T. theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. See provided URL for inquiries about permission. http://dspace.mit.edu/handle/1721.1/7582 124 leaves application/pdf Massachusetts Institute of Technology |
| spellingShingle | Mechanical Engineering. Shaltis, Phillip Andrew A wearable blood pressure sensor using oscillometric photoplethysmography and micro accelerometers |
| title | A wearable blood pressure sensor using oscillometric photoplethysmography and micro accelerometers |
| title_full | A wearable blood pressure sensor using oscillometric photoplethysmography and micro accelerometers |
| title_fullStr | A wearable blood pressure sensor using oscillometric photoplethysmography and micro accelerometers |
| title_full_unstemmed | A wearable blood pressure sensor using oscillometric photoplethysmography and micro accelerometers |
| title_short | A wearable blood pressure sensor using oscillometric photoplethysmography and micro accelerometers |
| title_sort | wearable blood pressure sensor using oscillometric photoplethysmography and micro accelerometers |
| topic | Mechanical Engineering. |
| url | http://hdl.handle.net/1721.1/40363 |
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