The effects of particle size of collagen and mold material on the pore structure of freeze-dried collagen-GAG scaffolds
Thesis (S.B.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2007.
| Main Author: | |
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| Other Authors: | |
| Format: | Thesis |
| Language: | eng |
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Massachusetts Institute of Technology
2008
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| Online Access: | http://hdl.handle.net/1721.1/40416 |
| _version_ | 1811085775934062592 |
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| author | Chan, Jenny K. (Jenny Kamjun) |
| author2 | Myron Spector. |
| author_facet | Myron Spector. Chan, Jenny K. (Jenny Kamjun) |
| author_sort | Chan, Jenny K. (Jenny Kamjun) |
| collection | MIT |
| description | Thesis (S.B.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2007. |
| first_indexed | 2024-09-23T13:15:29Z |
| format | Thesis |
| id | mit-1721.1/40416 |
| institution | Massachusetts Institute of Technology |
| language | eng |
| last_indexed | 2024-09-23T13:15:29Z |
| publishDate | 2008 |
| publisher | Massachusetts Institute of Technology |
| record_format | dspace |
| spelling | mit-1721.1/404162019-04-12T10:01:08Z The effects of particle size of collagen and mold material on the pore structure of freeze-dried collagen-GAG scaffolds Chan, Jenny K. (Jenny Kamjun) Myron Spector. Massachusetts Institute of Technology. Dept. of Mechanical Engineering. Massachusetts Institute of Technology. Dept. of Mechanical Engineering. Mechanical Engineering. Thesis (S.B.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2007. Includes bibliographical references (p. 25). This study was performed to determine whether the particle size of the starting collagen powder or the material of molds used during freeze-drying had effects on the scaffold pore structure. Collagen particles were separated by size prior to slurry making using a sieve with 1000 [mu]m openings, and scaffolds were made using both metal pans and polysulfone trays, two commonly used molds. The mean and variation of pore diameter and interconnectivity of freeze-dried scaffolds were compared to determine the relationship between particle size or mold material and the resulting pore diameter, for a specific same freeze-drying condition (viz., temperature). Knowing these relationships will permit a better control of pore size during fabrication, allowing researchers to design scaffolds with greater predictability and specificity. by Jenny K. Chan. S.B. 2008-02-27T22:22:57Z 2008-02-27T22:22:57Z 2007 2007 Thesis http://hdl.handle.net/1721.1/40416 191698827 eng M.I.T. theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. See provided URL for inquiries about permission. http://dspace.mit.edu/handle/1721.1/7582 25 p. application/pdf Massachusetts Institute of Technology |
| spellingShingle | Mechanical Engineering. Chan, Jenny K. (Jenny Kamjun) The effects of particle size of collagen and mold material on the pore structure of freeze-dried collagen-GAG scaffolds |
| title | The effects of particle size of collagen and mold material on the pore structure of freeze-dried collagen-GAG scaffolds |
| title_full | The effects of particle size of collagen and mold material on the pore structure of freeze-dried collagen-GAG scaffolds |
| title_fullStr | The effects of particle size of collagen and mold material on the pore structure of freeze-dried collagen-GAG scaffolds |
| title_full_unstemmed | The effects of particle size of collagen and mold material on the pore structure of freeze-dried collagen-GAG scaffolds |
| title_short | The effects of particle size of collagen and mold material on the pore structure of freeze-dried collagen-GAG scaffolds |
| title_sort | effects of particle size of collagen and mold material on the pore structure of freeze dried collagen gag scaffolds |
| topic | Mechanical Engineering. |
| url | http://hdl.handle.net/1721.1/40416 |
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